The effect of modifying dietary protein and carbohydrate in weight loss on arterial compliance and postprandial lipidemia in overweight women with polycystic ovary syndrome

Consensus on women’s health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group

“…Several studies report an association between weight or BMI and QOL scores (83,84) and recurrent major depressive disorder and social phobia (91). In an Australian study, the difference between PCOS and community controls in emotional disorder was attenuated after controlling for BMI (88)(89)(90). In two intervention studies, the extent of weight loss was associated with improvement in QOL (94,103).…”

“…More than 20 studies investigating specific impairments in patients with PCOS have been added to the literature since a 2006 review on specific disorders (74). Across these studies, which used questionnaires (86), structured psychiatric interviews (87), and Internet methods (84,85,(88)(89)(90), there is convergence that the prevalence of emotional disorders (depression, anxiety) is higher in patients with PCOS compared with healthy controls (85,(91)(92)(93) and compared with normative data from age-matched reference groups (83,93). Studies have replicated the greater prevalence of emotional disorders in adolescents (i.e., 12 to 18 years) (94)(95)(96) and younger women (i.e., 18 to 25 years) (88) compared with controls.…”

Effects of Lifestyle Modification on Pregnancy Success in Obese and Overweight Women with PCOS

“…Currently, there is limited evidence for specific dietary approaches in PCOS [34]. Only two controlled, randomized studies compared the effect of different long term diets in women with PCOS [35,36]. Both of these studies failed to prove significant differences in weight loss or reproductive outcome.…”

“…Both of these studies failed to prove significant differences in weight loss or reproductive outcome. Still, the authors concluded that low-fat diets produce a decrease in hyperinsulinemia, which improves metabolic effects [36].…”

“…In conclusion, low calorie diets (energy restriction of 500-600Kcal/per day) with reduced carbohydrate intake are recommended to obese women with PCOS. These diets with reduced glycemic load could be beneficial in alleviating hyperinsulinemia and its metabolic consequences [36]. The success of 5-10% loss of body weight and the effects on hyperinsulinemia are of particular significance to restoration of reproductive potential in women with PCOS [12,39].…”