The effect of mold sensitization and humidity upon allergic asthma

Hayes, Don; Jhaveri, Manan; Mannino, David M.; Strawbridge, Heather; Temprano, James

doi:10.1111/j.1752-699x.2012.00294.x

Cited by 37 publications

(22 citation statements)

References 52 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Interestingly, there have been no differences in controlled asthma between seasonal or perennial allergens. When comparing perennial allergens, Alternaria ‐allergic patients with asthma show a worse level of controlled disease (based on GEMA guidelines) in concordance with previous reports in adults . In fact, fungal sensitization has been associated with increased asthma morbidity and mortality, including higher rates of hospitalization .…”

Section: Discussionsupporting

confidence: 82%

Allergic respiratory disease: Different allergens, different symptoms

Valero

Quirce

Dávila

et al. 2017

Allergy

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 82%

Allergic respiratory disease: Different allergens, different symptoms

Valero

Quirce

Dávila

et al. 2017

Allergy

View full text Add to dashboard Cite

show abstract

“…Conversely, a Japanese study demonstrated an association between low relative humidity and hospital admissions for paediatric asthma admissions. Indirect effects of humidity on respiratory disease include the role of moist indoor environments in promoting the growth of mold and the reproduction of mites (Hayes et al, 2013;Richardson et al, 2005;Williamson et al, 1997) and the effects of humidity on pollen dispersal and pollen-related allergens (Bartkova-Scevkova, 2003). In a series of controlled climate chamber studies on exercise performance (Eschenbacher et al, 1992), asthma patients exhibited significantly greater bronchoconstriction after exercise than non-asthmatic subjects as RH decreased.…”

Section: Humidity and Pulmonary Diseasementioning

confidence: 99%

Humidity: A review and primer on atmospheric moisture and human health

Davis

McGregor

Enfield

2016

Environmental Research

344

208

View full text Add to dashboard Cite

Use policyThe full-text may be used and/or reproduced, and given to third parties in any format or medium, without prior permission or charge, for personal research or study, educational, or not-for-prot purposes provided that:• a full bibliographic reference is made to the original source • a link is made to the metadata record in DRO • the full-text is not changed in any way The full-text must not be sold in any format or medium without the formal permission of the copyright holders.Please consult the full DRO policy for further details. cases when the proximity to saturation is not medically relevant. Care must be taken in averaging certain humidity variables daily or seasonally to avoid statistical biasing associated with variables that are inherently diurnal through their relationship to temperature.

show abstract

“…The provision of evidence linking damp indoor environments and fungal diversity to adverse health outcomes has practical implications by informing future health interventions. For example, these could be used to target high‐risk populations such as those sensitized to specific fungi that are more likely to suffer from severe asthma , households with infants, and other important fungal‐related health problems. These may include life threatening infections, allergic bronchopulmonary aspergillosis, aspergilloma (fungus ball), invasive pulmonary aspergillosis, chronic necrotizing aspergillosis and allergic fungal rhinosinusitis , not reviewed here.…”

Section: Indoor Damp Fungi and Risk Of Asthmamentioning

confidence: 99%

Modifiable factors governing indoor fungal diversity and risk of asthma

Sharpe

Thornton

Osborne

2014

Clin Experimental Allergy

View full text Add to dashboard Cite

Exposure to dampness and fungi in the home is a known risk factor for individuals with allergic asthma. Inadequate heating and ventilation may lead to dampness and concomitant increased exposure to spores of allergenic fungi such as Aspergillus and Penicillium. These fungi have been cultured from sputum of asthmatic and non-asthmatic individuals, and implicated in the initiation or exacerbation of asthma. Indoor environmental factors influence the presence and concentrations of fungal propagules and, in turn, risk of asthma outcomes. This review aims to identify modifiable risk factors in the built environment that have been shown to influence fungal composition indoors, and to examine this association with the risk of asthma development and/or exacerbation. A complex interaction between residential characteristics, the built environment and the behaviour of people regulate the diversity and concentrations of indoor fungi. Modifiable factors include build age, architectural design, level of maintenance, variations in construction materials, presence of pets, heating and ventilation patterns. Risk of fungal contamination and asthma outcomes are also influenced by low occupant awareness concerning potential health effects and socio-economic factors. Addressing these factors provides an opportunity to improve future housing interventions, though it is not clear how the built environment and occupant behaviours interact to modify the diversity of indoor fungi and resultant risk of asthma. A combination of housing improvements combined with awareness programmes and the alleviation of fuel poverty can be used to lower the allergen burden associated with damp homes. Further research is needed to identify factors that regulate the concentration and diversity of indoor fungi and how this may act as a modifier for asthma outcomes.

show abstract

The effect of mold sensitization and humidity upon allergic asthma

Cited by 37 publications

References 52 publications

Allergic respiratory disease: Different allergens, different symptoms

Allergic respiratory disease: Different allergens, different symptoms

Humidity: A review and primer on atmospheric moisture and human health

Modifiable factors governing indoor fungal diversity and risk of asthma

Contact Info

Product

Resources

About