The Effect of Nasal Septal Perforation and its Treatment on Objective Sleep and Breathing Parameters

Abstract

BackgroundNasal septal perforation (NSP) may alter nasal airflow patterns and physiology. To the best of our knowledge, no studies in the English literature have investigated the effect of NSP and its treatment on polysomnographic parameters. In this study, we aimed to investigate polysomnographic parameters in patients with NSP as well as changes in those parameters after treatment of NSP.Material/MethodsNineteen patients diagnosed with NSP were included in the study. All patients had baseline and post-procedure polysomnographies (PSG) after insertion of silicone septal button for closure of NSP.ResultsBoth median AHI [5.30 (14.40) vs. 2.40 (14.50)] and median supine AHI [10.00 (42.10) vs. 6.60 (37.00)] decreased after correction of the perforation. There was a large reduction in median supine AHI in patients with a perforation size >66 mm2 [10.10 (34.15) vs. 1.60 (28.30)].ConclusionsWe conclude that NSP did not cause any deterioration in objective sleep parameters as determined by PSG, other than a decrease in REM sleep duration and an increase in supine AHI. Correction of NSP did not affect REM duration and supine AHI decreased after treatment.

Custom Nasal Septum Prosthesis Fabricated from a 3D‐Printed Working Model: A Clinical Report

“…The patient's chief concern in this current report was related to the use of her CPAP machine at night and not achieving a proper seal due to her nasal septum perforation. Boynuegri et al studied the effects of nasal septum perforations on objective sleep and breathing parameters. The study followed 19 patients with nasal septum perforations before and after being repaired by silicone buttons and found no deterioration in objective sleep parameters .…”

“…Boynuegri et al studied the effects of nasal septum perforations on objective sleep and breathing parameters. The study followed 19 patients with nasal septum perforations before and after being repaired by silicone buttons and found no deterioration in objective sleep parameters . Although there is no evidence to suggest nasal perforations have a negative impact on sleep parameters, in this patient it did address her chief concern, and minimized the symptoms of dryness, bleeding, and crusting.…”

In Vivo Biocompatibility and Biodegradability of Bilayer Films Based on Hyaluronic Acid and Chitosan for Ear, Nose and Throat Surgery

“…), intranasal synthetic steroids (mometasone, budesonide, beclomethasone, fluticasone, etc.) [2][3][4], other topical drugs (e.g., desmopressin against diabetes insipidus [5]), prolonged recovery period after septoplasty (e.g., for crooked nasal septum treatment) [6] and serious trauma with massive cartilage destruction [7]. Under these Eng.…”

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“…Nasal septal perforations are a relatively uncommon pathology that can occur due to trauma, iatrogenic causes, and inhalation drug use among others. 1,2 Perforations can cause symptoms of chronic epistaxis, nasal crusting, congestion, and whistling when breathing. 2 These symptoms can significantly impact patient quality of life.…”