The Effect of Nursing Interventions on Catheter-related Bloodstream Infections in Patients Receiving Total Parenteral Nutrition Through Peripherally Inserted Central Catheter Lines

Abstract

Background: Catheter-related blood-stream infection (CRBSI) is a serious and costly complication associated with central venous catheters. Nursing interventions that focus on decreasing bacterial colonization at the insertion site could decrease infection rates. Method: This retrospective study examined CRBSI in patients requiring peripherally inserted central catheters (PICCs) for total parenteral nutrition. One hundred and ninety-two patients with 235 catheters and an average dwell time of 11.5 days participated. Nursing interventions included a chlorhexidine-impregnated sponge dressing and a double skin scrub prior to insertion. Conclusion: The results of the study show that the interventions did not reduce CRBSI in the target population but the double skin scrub did decrease CRBSI in the general PICC population.

Does Parenteral Nutrition Increase the Risk of Catheter‐Related Bloodstream Infection? A Systematic Literature Review

“…Blood products were administered in 3 studies 36 , 40 , 43 . Antibiotics were administered in 3 studies 36 , 37 , 39 (see Table 3).…”

“…Eight studies were rated as moderate risk of bias, 2 as serious, and 1 as critical. Three studies were rated as serious bias in the confounding domain 34 , 36 , 37 . Differences between the intervention and the control group characteristics were not accounted for in the study design.…”

“…The studies were published between 1986 and 2014. The studies were carried out in 3 countries: United States (n = 6), 33 – 38 Brazil (n = 1), 39 and France (n = 4) 40 – 43 . Six studies reported both the number of patients and CVADs enrolled 34 – 36 , 39 , 40 , 43 .…”

“…There were 2854 patients enrolled in the 9 studies 33 – 36 , 39 – 43 that provided this information; these numbers ranged from 74 to 831. There were 6287 CVADs described in 8 studies 34 – 40 , 43 . Two studies 37 , 38 only reported number of CVADs and therefore may have included participants with multiple CVADs.…”

“…There were 6287 CVADs described in 8 studies 34 – 40 , 43 . Two studies 37 , 38 only reported number of CVADs and therefore may have included participants with multiple CVADs. Characteristics of the 11 included studies are summarized in Table 1.…”