The Effect of Obesity on Renal Transplant Outcomes

Dw, Johnson; Isbel, N.; Td, Kay; Hawley, C. M.; Sb, Campbell; Dl, Nicol

doi:10.1046/j.1440-1797.2002.00007-1-39.x

Cited by 2 publications

(3 citation statements)

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“…The influence of obesity on outcomes after solid organ transplantation remains controversial (12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25). In a large retrospective multi-institutional study by Grady et al (21) data of 4515 HTX recipients were collected.…”

Section: Discussionmentioning

confidence: 99%

The impact of overweight on the development of diabetes after heart transplantation

Kahn

Rehak

Schweiger

et al. 2005

Clinical Transplantation

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Section: Discussionmentioning

confidence: 99%

The impact of overweight on the development of diabetes after heart transplantation

Kahn

Rehak

Schweiger

et al. 2005

Clinical Transplantation

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“…A negative impact of obesity on patient survival after transplant has been shown in some (5,9) but not in other (10,11) investigations. In most of these studies, the impact of obesity on CV events was not emphasized or even evaluated.…”

Section: Discussionmentioning

confidence: 94%

“…They also reviewed recent literature on the subject and considered that findings for coronary/ischemic outcomes were inconsistent. The latter finding may be caused by exclusion of patients with significant CV disease from waiting lists in some centers (11), a policy that we do not follow (7). In our center, we do not consider obesity or CV disease absolute contraindications for renal transplantation.…”

Section: Discussionmentioning

confidence: 95%

Coronary events in obese hemodialysis patients before and after renal transplantation

Lima

Gowdak

Paula

et al. 2015

Clinical Transplantation

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We examined the impact of obesity (BMI ≥30 kg/m(2) , n = 357) on prognosis in 1696 hemodialysis (HD) patients before and after renal transplantation (TX). End-points were coronary events, composite cardiovascular (CV) events, and death. Obese HD patients were older (55.9 ± 9.2 vs. 54.2 ± 11), had more diabetes (54% vs. 40%), dyslipidemia (49% vs. 30%), altered myocardial scan (38% vs. 31%), myocardial infarction (MI) (16% vs. 10%), coronary intervention (11% vs. 7%), higher total cholesterol (186 ± 52 vs. 169 ± 47), and triglycerides (219 ± 167 vs. 144 ± 91). Obese undergoing TX had more dyslipidemia (46% vs. 31%), angina (23% vs. 14%), MI (18% vs. 5%), increased total cholesterol (185 ± 56 vs. 172 ± 48), and triglycerides (237 ± 190 vs. 149 ± 100). Obesity was independently associated with coronary events (log-rank = 0.008, HR 2.55% CI 1.27-5.11) and death (log-rank 0.046, HR 1.52, % CI 1.007-2.30) in TX but not in HD. Obese HD patients had more risk factors and ischemic heart disease, but these characteristics did not interfere with prognosis. In TX patients, obesity predicts coronary events and death.

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The Effect of Obesity on Renal Transplant Outcomes

Cited by 2 publications

References 0 publications

The impact of overweight on the development of diabetes after heart transplantation

The impact of overweight on the development of diabetes after heart transplantation

Coronary events in obese hemodialysis patients before and after renal transplantation

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