The effect of ovariectomy on cardiac autonomic control in rats submitted to aerobic physical training

Tezini, Geisa C.S.V.; Silveira, Larissa C.R.; Maida, K; Blanco, João Henrique Dutra; Souza, Hugo Celso Dutra de

doi:10.1016/j.autneu.2008.05.003

Cited by 11 publications

(11 citation statements)

References 60 publications

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“…With the two active groups having similar fitness, it is therefore unlikely that exercise training intensity per se can account for the augmented vagal modulation of HR in ExFHA women. Interestingly, the present finding is consistent with reports of augmented cardiac vagal modulation of HR in aerobically trained ovariectomized versus intact rats [41,42], suggesting that hypoestrogenemia may modulate exercise-training induced effects on parasympathetic HR modulation. Examination of such postulates awaits delineation.…”

Section: Exercise Training and Hr Modulationsupporting

confidence: 82%

Augmented vagal heart rate modulation in active hypoestrogenic pre-menopausal women with functional hypothalamic amenorrhoea

et al. 2015

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Section: Exercise Training and Hr Modulationsupporting

confidence: 82%

Augmented vagal heart rate modulation in active hypoestrogenic pre-menopausal women with functional hypothalamic amenorrhoea

et al. 2015

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“…Moreover, changes in the spectral parameters for R-R interval (Table 2) and autonomic tone (Fig. 1B) induced by the exercise training are consistent with earlier studies in rats (30,31).…”

Section: Validity Of Exercise Trainingsupporting

confidence: 90%

Exercise training augments the dynamic heart rate response to vagal but not sympathetic stimulation in rats

Mizuno

Kawada

Kamiya

et al. 2011

American Journal of Physiology-Regulatory, Integrative and Comp

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We examined the transfer function of autonomic heart rate (HR) control in anesthetized sedentary and exercise-trained (16 wk, treadmill for 1 h, 5 times/wk at 15 m/min and 15-degree grade) rats for comparison to HR variability assessed in the conscious resting state. The transfer function from sympathetic stimulation to HR response was similar between groups (gain, 4.2 ± 1.5 vs. 4.5 ± 1.5 beats·min(-1)·Hz(-1); natural frequency, 0.07 ± 0.01 vs. 0.08 ± 0.01 Hz; damping coefficient, 1.96 ± 0.55 vs. 1.69 ± 0.15; and lag time, 0.7 ± 0.1 vs. 0.6 ± 0.1 s; sedentary vs. exercise trained, respectively, means ± SD). The transfer gain from vagal stimulation to HR response was 6.1 ± 3.0 in the sedentary and 9.7 ± 5.1 beats·min(-1)·Hz(-1) in the exercise-trained group (P = 0.06). The corner frequency (0.11 ± 0.05 vs. 0.17 ± 0.09 Hz) and lag time (0.1 ± 0.1 vs. 0.2 ± 0.1 s) did not differ between groups. When the sympathetic transfer gain was averaged for very-low-frequency and low-frequency bands, no significant group effect was observed. In contrast, when the vagal transfer gain was averaged for very-low-frequency, low-frequency, and high-frequency bands, exercise training produced a significant group effect (P < 0.05 by two-way, repeated-measures ANOVA). These findings suggest that, in the frequency domain, exercise training augments the dynamic HR response to vagal stimulation but not sympathetic stimulation, regardless of the frequency bands.

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“…Exercise training promotes an increase in the capacity of the ANS to meet the demands of the cardiovascular system, thereby increasing heart rate variability (HRV) (16)(17)(18). One of the methods of studying autonomic modulation is by spectral analysis.…”

Section: Cardiovascular and Autonomic Adaptations To Exercise Trainingmentioning

confidence: 99%

Cardiovascular and autonomic modulation by the central nervous system after aerobic exercise training

Martins‐Pinge

2011

Braz J Med Biol Res

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The autonomic nervous system plays a key role in maintaining homeostasis under normal and pathological conditions. The sympathetic tone, particularly for the cardiovascular system, is generated by sympathetic discharges originating in specific areas of the brainstem. Aerobic exercise training promotes several cardiovascular adjustments that are influenced by the central areas involved in the output of the autonomic nervous system. In this review, we emphasize the studies that investigate aerobic exercise training protocols to identify the cardiovascular adaptations that may be the result of central nervous system plasticity due to chronic exercise. The focus of our study is on some groups of neurons involved in sympathetic regulation. They include the nucleus tractus solitarii, caudal ventrolateral medulla and the rostral ventrolateral medulla that maintain and regulate the cardiac and vascular autonomic tonus. We also discuss studies that demonstrate the involvement of supramedullary areas in exercise training modulation, with emphasis on the paraventricular nucleus of the hypothalamus, an important area of integration for autonomic and neuroendocrine responses. The results of these studies suggest that the beneficial effects of physical activity may be due, at least in part, to reductions in sympathetic nervous system activity. Conversely, with the recent association of physical inactivity with chronic disease, these data may also suggest that increases in sympathetic nervous system activity contribute to the increased incidence of cardiovascular diseases associated with a sedentary lifestyle.

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The effect of ovariectomy on cardiac autonomic control in rats submitted to aerobic physical training

Cited by 11 publications

References 60 publications

Augmented vagal heart rate modulation in active hypoestrogenic pre-menopausal women with functional hypothalamic amenorrhoea

Augmented vagal heart rate modulation in active hypoestrogenic pre-menopausal women with functional hypothalamic amenorrhoea

Exercise training augments the dynamic heart rate response to vagal but not sympathetic stimulation in rats

Cardiovascular and autonomic modulation by the central nervous system after aerobic exercise training

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