The Effect of Percutaneous Coronary Intervention on Left Ventricular Diastolic Dysfunction in Patients with Coronary Artery Disease Assessed by Strain Rate Imaging

Bayat, Fariba; Farahani, Elham; Saadat, Habibollah

doi:10.4236/wjcd.2014.410063

Cited by 4 publications

(2 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Similar pattern of change in Mitral inflow parameters was seen in the study by Mandal et al 16 Mean On a whole, our study showed that the changes in E/A ratio, A wave duration, Deceleration time, A' velocity, E/E' ratio, Ar-A duration, and E/Vp showed significance but the changes in E velocity, A velocity, E' velocity, IVRT, and Vp did not showed no significance. Study by Bayat et al 17 demonstrated improvement in regional LV early diastolic function after PCI and except pulmonary vein flow all of the left ventricular diastolic parameters such as Mitral E velocity, Mitral A velocity, mitral E' septal, E/E′ ratio, IVRT and E/A ratio showed significant improvement after elective PCI. In a similar study Hashemi et al 18 evaluated diastolic echocardiographic findings before PCI, 48 hours and 3 months after PCI in 30 patients with EF of more than 40% scheduled for elective PCI.…”

Section: Discussionmentioning

confidence: 90%

Echocardiographic Evaluation of Left Ventricular Diastolic Function after Percutaneous Coronary Intervention in Patients with Acute STEMI

Kavirayani¹,

Gudivada²

2020

jebmh

View full text Add to dashboard Cite

BACKGROUND Although percutaneous coronary intervention (PCI) is an excellent therapy for coronary artery disease, the effects of PCI on left ventricular diastolic function have not been systematically investigated in patients of Acute ST Elevation Myocardial Infarction (STEMI) in our population. The aim of this study was to investigate the reversibility of these diastolic abnormalities and improvement in left ventricular diastolic function by using echocardiographic diastolic parameters in patients with Acute STEMI in the setting of PCI and thus determine the effects of improved myocardial perfusion on impaired left ventricular diastolic abnormalities. METHODS A total of 100 consecutive patients admitted to Intensive Coronary Care Unit (ICCU), was included in the study. Echocardiography was done before PCI and 48 hours after PCI, to evaluate the indices of LV diastolic function in these patients. RESULTS The mean age of the patients was 52.04 ± 9.49 years, and majority of patients were males (84%). All had mild to moderate degree of left ventricular diastolic dysfunction. Mitral E wave velocity (63.41 cm/s ± 19.93 before treatment versus 71.51 cm/s ± 9.56, 48 hours after treatment), the peak velocity of late filling due to atrial contraction (mitral A wave velocity) (75.93 cm/s ± 20.3 before treatment vs. 78.96 cm/s ± 24.18, 48 hours after treatment), E/A ratio (1.03 ± 0.3 before treatment vs. 0.98 ± 0.24, 48 hours after treatment) showed improvement after PCI. After PCI deceleration time (DT) decreased (210.15 msec ± 47.43 before treatment versus 201.64 msec ± 28.15, 48 hours after treatment), and the difference was statistically significant (p<0.001). It is notable that early diastolic mitral annular velocity (E') improved significantly 48 hours after PCI (5.81 cm/s ± 1.65 before treatment vs. 7.96 cm/s ± 1.95, 48 hours after treatment, p < 0.001). E/ E2 ratio showed significant change 48 hours after PCI; it was statistically significant (10.17 ± 2.26 before treatment vs. 8.83 ± 1.7, 48 hours after treatment p<0.001). CONCLUSIONS Improvement in some indices of left ventricular diastolic function after PCI suggests that PCI can be an effective modality of treatment for diastolic dysfunction caused by myocardial ischemia and revascularization can restore diastolic properties of the heart after the insult in STEMI patients and thus prevent their progression to HFPEF.

show abstract

Section: Discussionmentioning

confidence: 90%

Echocardiographic Evaluation of Left Ventricular Diastolic Function after Percutaneous Coronary Intervention in Patients with Acute STEMI

Kavirayani¹,

Gudivada²

2020

jebmh

View full text Add to dashboard Cite

show abstract

“…Bayat et al (23) found that improvement in global LV early diastolic filling after PCI was associated with the degree to which impaired regional myocardial relaxation improved in the ischemic segments.…”

Section: Discussionmentioning

confidence: 99%

Assessment of Left Atrial Function After Percutaneous Coronary Intervention: A Doppler-Based Strain and Strain Rate Study

Bayat¹,

Nazmdeh²,

Safi³

et al. 2015

Arch Cardiovasc Imaging

Self Cite

View full text Add to dashboard Cite

Background: Left atrial function can be critical for risk assessment and prediction of adverse cardiac events. Tissue Doppler of atrial contraction can provide regional and global snapshots of atrial systolic function. Objectives: The present study aimed to assess left atrial function by tissue Doppler parameters of strain and strain rate following percutaneous coronary intervention (PCI). Patients and Methods:This prospective study recruited 77 consecutive patients with coronary artery disease who underwent PCI. The study end point was to assess left atrial function by regional strain and strain rate parameters before and after PCI via tissue Doppler imaging. Results: Regarding changes in left trial functional parameters after PCI, those such as the strain of the septal wall and the anterior and inferior walls and the strain rate of the anterior and lateral walls significantly increased following PCI, while the strain of the lateral wall and the strain rate of the septal wall significantly decreased. Conclusions: PCI was accompanied by some improvement in left atrial deformation indices as assessed by tissue Doppler imaging. Revascularization can, therefore, improve patient outcome.

show abstract

Effect of Primary Stenting of Coronary Arteries on Clinical Course and Remodeling of the Left Ventricle in Patients With Acute St Segment Elevation Myocardial Infarction (Results After 12 Months)

et al. 2020

View full text Add to dashboard Cite

The aim: To determine the predictive effect of primary stenting of coronary artery on the clinical course and features of left ventricular remodeling in patients with acute myocardial infarction (MI) with ST segment elevation and LV diastolic dysfunction (DD) in the remote period (12 months). Materials and methods: The study included 80 patients with STEMI who undergo primary PCI (group 1) and 20 patients with STEMI who did not undergo myocardial revascularization (group 2). In both groups, the levels of NT-proBNP were determined, echocardiography, bicycle ergometry; quality of life was determined according to SAQ questionnaire scales; marked cardiovascular complications. Patients were re-examined after 12 months. Results: The average level of NT-proBNP for 5 days and 12 months of patients in group 1 significantly decreased – 434.6 ± 36.3 and 122.8 ± 4.13 g / ml (p <0.001), indicating a less pronounced late remodeling of LV in patients undergoing revascularization with STEMI. Diastolic function was evaluated by E/A and DT. After 12 months, the 1st group was markedly lower than E/A and DT compared to the 2nd – 0.76 ± 0.03 and 198 ± 4.7 m / s and 1.49 ± 0.01 and 135 , 3 ± 2.91 m/s, respectively (p <0.05), which characterizes a decrease in the parameters of the DD by the type of the relaxation processes of the left ventriculi. Patients in Group 1, according to SAQ scales, had better quality of life and higher exercise tolerance at I-II level than patients without revascularization. Conclusions: In patients with STEMI, after a primary stenting of coronary artery, a significantly lower NT-proBNP level and less pronounced DD manifestations in the long-term (12 months) period demonstrated a better tolerance to physical activity and improved quality of life, as determined by the SAQ questionnaire and a lower rate of development cardiovascular complications.

show abstract

The Effect of Percutaneous Coronary Intervention on Left Ventricular Diastolic Dysfunction in Patients with Coronary Artery Disease Assessed by Strain Rate Imaging

Cited by 4 publications

References 30 publications

Echocardiographic Evaluation of Left Ventricular Diastolic Function after Percutaneous Coronary Intervention in Patients with Acute STEMI

Echocardiographic Evaluation of Left Ventricular Diastolic Function after Percutaneous Coronary Intervention in Patients with Acute STEMI

Assessment of Left Atrial Function After Percutaneous Coronary Intervention: A Doppler-Based Strain and Strain Rate Study

Effect of Primary Stenting of Coronary Arteries on Clinical Course and Remodeling of the Left Ventricle in Patients With Acute St Segment Elevation Myocardial Infarction (Results After 12 Months)

Contact Info

Product

Resources

About