The effect of percutaneous dilatation of renal arterial stenosis on captopril renography in hypertension

Anfelter, Peter; Granérus, Göran; Stenström, Hugo; Eriksson, Per; Nyström, Fredrik

doi:10.1080/08037050500339275

Cited by 2 publications

(1 citation statement)

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“…In the group of subjects with the preserved renal function, the sensitivity and specificity were approximately 90%, while in the group of patients with the impaired renal function the tests showed lower specificity 11,14,15 . In addition, some case studies point out the potential role of the captopril scintigraphy in the evaluation of the effects of percutaneous transluminal dilatation of renal artery stenosis in hypertension 16 . In the presented case, the captopril scintigraphy, performed immediately after the endovascular procedure, indicated significantly improved parenchymal indicators of the right kidney which corresponded to a complete normalization of the patient's blood pressure occurring several months after the scintigraphy.…”

Section: Discussionmentioning

confidence: 99%

The role of a captopril renal scintigraphy in examination of children with hypertension: A case report

et al. 2018

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Introduction. Secondary hypertension is a relatively common form of hypertension in childhood with renovascular hypertension being responsible for 5%-10% of all arterial hypertensions in children. An early diagnosis of renovascular hypertension is important when considering an appropriate treatment of hypertension that may prevent or slow further progression of kidney damage. To validate the usefulness of a captopril renal scintigraphy in hypertensive children, we report a case of a 16-year-old female patient with a history of hypertension as a result of fibromuscular dysplasia. Case report. The patient was asymptomatic with elevated blood pressure revealed by a routine physical examination. Laboratory tests showed the increased levels of plasma renin activity with the normal levels of aldosteron. The renal ultrasound was normal. The Doppler of the renal arteries showed no significant differences of resistive index. A renal captopril scintigraphy was performed, including two day study protocol, the baseline study followed by another captopril study several days later. The scintigraphy showed the abnormal baseline and captopril renogram curve of the right kidney with significant cortical retention of radiotracer after angiotensin-converting enzyme inhibition. Following the captopril scintigraphy a renovasography was obtained confirming the presence of a 2 mm long circular narrowing of the right renal artery. It was immediately treated resulting in a significant expansion of the lumen. Conclusion. The captopril renal scintigraphy allows non-invasive functional testing in a selected group of hypertensive children, which can either confirm or rule out the existence of hemodynamically significant renal artery stenosis.

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Section: Discussionmentioning

confidence: 99%