The Effect of Periprocedural Clinical Factors Related to the Course of STEMI in Men and Women Based on the National Registry of Invasive Cardiology Procedures (ORPKI) between 2014 and 2019

Sielski, Janusz; Kaziród-Wolski, Karol; Jurys, Karolina; Wałek, Paweł; Siudak, Zbigniew

doi:10.3390/jcm10235716

Cited by 5 publications

(4 citation statements)

References 49 publications

(46 reference statements)

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“…The analysis of a large number of variables in scientific studies requires the creation of new statistical tools. Logistic regression seems to be a promising tool in this analysis and has been successfully used by authors [ 28 , 49 ]. An even more interesting statistical tool for the analysis of large amounts of data with the use of long-term databases is the creation of neural networks.…”

Section: Discussionmentioning

confidence: 99%

“…A study of patients with ACS and the impact of vaccination was presented by our research team in another paper [ 26 ]. Correlations between acute coronary syndromes and various clinical, peri-procedural, and environmental factors have been studied by our team for several years [ 15 , 27 , 28 ]. The current work presents for the first time the correlations between environmental factors (air pollution and COVID-19 infection).…”

Section: Methodsmentioning

confidence: 99%

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Impact of Air Pollution and COVID-19 Infection on Periprocedural Death in Patients with Acute Coronary Syndrome

Sielski

Jóźwiak²,

Kaziród-Wolski

et al. 2022

IJERPH

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Air pollution and COVID-19 infection affect the pathogenesis of cardiovascular disease. The impact of these factors on the course of ACS treatment is not well defined. The purpose of this study was to evaluate the effects of air pollution, COVID-19 infection, and selected clinical factors on the occurrence of perioperative death in patients with acute coronary syndrome (ACS) by developing a neural network model. This retrospective study included 53,076 patients with ACS from the ORPKI registry (National Registry of Invasive Cardiology Procedures) including 2395 COVID-19 (+) patients and 34,547 COVID-19 (-) patients. The neural network model developed included 57 variables, had high performance in predicting perioperative patient death, and had an error risk of 0.03%. Based on the analysis of the effect of permutation on the variable, the variables with the greatest impact on the prediction of perioperative death were identified to be vascular access, critical stenosis of the left main coronary artery (LMCA) or left anterior descending coronary artery (LAD). Air pollutants and COVID-19 had weaker effects on end-point prediction. The neural network model developed has high performance in predicting the occurrence of perioperative death. Although COVID-19 and air pollutants affect the prediction of perioperative death, the key predictors remain vascular access and critical LMCA or LAD stenosis.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Impact of Air Pollution and COVID-19 Infection on Periprocedural Death in Patients with Acute Coronary Syndrome

Sielski

Jóźwiak²,

Kaziród-Wolski

et al. 2022

IJERPH

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“…Electronic data were collected from patients with acute coronary syndromes who underwent invasive cardiology procedures. This study included data from patients enrolled in the register between 2014 and 2021 [ 8 , 9 ]. We determined the number of patients undergoing PCI following admission with ACS (STEMI, NSTEMI, or UA) during the day of autumn and spring time change.…”

Section: Methodsmentioning

confidence: 99%

The Effect of Daylight-Saving Time on Percutaneous Coronary Intervention Outcomes in Acute Coronary Syndrome Patients—Data from the Polish National Registry of Percutaneous Coronary Interventions (ORPKI) in the Years 2014–2022

Kaziród-Wolski,

Piotrowska,

Sielski

et al. 2023

JCDD

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Introduction: Many factors related to the switch to summer/winter time interfere with biological rhythms. Objectives: This study aimed to analyze the impact of time change on clinical outcomes of patients with acute coronary syndromes (ACS) undergoing percutaneous coronary intervention (PCI). Patients and methods: Electronic data of 874,031 patients with ACS who underwent invasive procedures were collected from the Polish National Register of Interventional Cardiology Procedures (ORPKI) between 2014 and 2021. We determined the number of patients undergoing PCI and periprocedural mortality during the day of spring or autumn time change and within the first 3 and 7 days after the time change. Results: We demonstrated the impact of time changes on the periprocedural mortality of ACS patients within 1 day and the period of 3 and 7 days from the time change. We observed that the occurrence of all ACS and NSTEMI on the first day was lower for both time changes and higher in the case of UA and spring time change. The autumn time change significantly reduced the occurrence of all types of ACS. A significant decrease in the number of invasive procedures was found after autumn transition in the period from the first day to 7 days for ACS, NSTEMI, and UA. Conclusions: The occurrence of ACS and the number of invasive procedures were lower for both changes over time. Autumn time change is associated with increased periprocedural mortality in ACS and a less frequent occurrence of UA and NSTEMI within 7 days.

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“…Previous studies have consistently reported that female patients with acute myocardial infarction (AMI) have higher unadjusted mortality rates than men, especially for short-term follow-up [1,2]. Women present with AMI at a later age, with greater cardiovascular risk burdens, and with less opportunity to receive guideline-recommended therapies.…”

Section: Introductionmentioning

confidence: 99%

Gender Differences in All-Cause Mortality after Acute Myocardial Infarction: Evidence for a Gender–Age Interaction

Song

Kim

Seong

et al. 2022

JCM

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Gender difference studies in mortality after acute myocardial infarction (AMI) have shown inconsistent results. A total of 13,104 patients from the KAMIR-NIH between November 2011 and December 2015 were classified into young (n = 3837 [29.3%]) and elderly (n = 9267 [70.7%]) patients. For the study, women <65 and men <55 years of age were considered “young”. In the adjusted model of the entire cohort, there was no significant difference in three-year all-cause mortality between women and men (17.8% vs. 10.3%; adjusted hazard ratio [HR], 0.953; 95% confidence interval [CI], 0.799–1.137). However, when the entire cohort was subdivided into two age groups, young women showed an 84.3% higher mortality rate than young men (adjusted HR, 1.843; 95% CI, 1.098–3.095). Contrariwise, elderly women patients had a 20.4% lower hazard of mortality compared with elderly men (adjusted HR, 0.796; 95% CI, 0.682–0.929). The interaction of gender with age was significant, even after multiple adjustments (adjusted p for interaction = 0.003). The purpose of this study was to assess whether gender differences depend on the patients’ age. Based on our analysis, higher mortality of young women remains even in the contemporary era of AMI. A better understanding of the mechanisms underlying these differences is warranted.

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The Effect of Periprocedural Clinical Factors Related to the Course of STEMI in Men and Women Based on the National Registry of Invasive Cardiology Procedures (ORPKI) between 2014 and 2019

Cited by 5 publications

References 49 publications

Impact of Air Pollution and COVID-19 Infection on Periprocedural Death in Patients with Acute Coronary Syndrome

Impact of Air Pollution and COVID-19 Infection on Periprocedural Death in Patients with Acute Coronary Syndrome

The Effect of Daylight-Saving Time on Percutaneous Coronary Intervention Outcomes in Acute Coronary Syndrome Patients—Data from the Polish National Registry of Percutaneous Coronary Interventions (ORPKI) in the Years 2014–2022

Gender Differences in All-Cause Mortality after Acute Myocardial Infarction: Evidence for a Gender–Age Interaction

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