2008
DOI: 10.1016/j.biomaterials.2008.06.014
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The effect of platelet-rich plasma on healing in critical-size long-bone defects

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Cited by 200 publications
(212 citation statements)
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References 48 publications
(76 reference statements)
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“…Mouse: [223] (hVEGF/hMPC), [224] (hVEGF/hBMP2/hMPC) Rat: [225] (hBMP2/hMPC), [226] (hBMP7/hMPC) Rabbit: [227], [228] (PRP/rbMPC),…”
Section: Mpcs With Growth Factors/compoundsmentioning
confidence: 99%
“…Mouse: [223] (hVEGF/hMPC), [224] (hVEGF/hBMP2/hMPC) Rat: [225] (hBMP2/hMPC), [226] (hBMP7/hMPC) Rabbit: [227], [228] (PRP/rbMPC),…”
Section: Mpcs With Growth Factors/compoundsmentioning
confidence: 99%
“…Some studies have affirmed that α-TCP cement not only is biocompatible but also is bioconductive and bioactive (20,25,30,31) . There is evidence that the growth factors obtained from PRP may regulate the reconstruction and physiological bone remodeling, and are a powerful form of treatment in lesion repair (10,18,(32)(33)(34)(35) . In the light of these precepts, combined application of α-TCP cement and PRP seems to fit the ideal properties characterizing these interactions.…”
Section: Radiographic and Histological Resultsmentioning
confidence: 99%
“…White et al (2000) describe that the use of other anticoagulants such as EDTA can cause structural and functional damage to platelets, and also may later cause damage to the treated tissues, suggesting that the choice of sodium citrate was the better option. On the other hand, use of other anticoagulants such as citrate dextrose solution (Lu et al 2008) and heparin (Kasten et al 2008) are described by other authors. Thus, this study followed the same protocol of Barboza et al (2008) and Vanat et al (2012) to using sodium citrate tubes.…”
Section: Discussionmentioning
confidence: 99%