The Effect of Platelete Rich Plasma Combined with Microneedling on Full Venous Outflow Compromise in a Rat Skin Flap Model

Evaluation of Micro-Needling as a Flap Preconditioning Modality: A Split-Flap Study

“…They concluded that micro-needling combined with PRP might be an effective treatment modality to reduce congestion, interstitial edema and increase neoangiogenesis in venous congested skin flaps. Their results suggested that the growth factors that might be released from activated platelets in addition to the micro-needling induced sensory nerve fibers' activation, increase tissue survival and regeneration [14].…”