The effect of porosity on the mechanical properties of 3D-printed triply periodic minimal surface (TPMS) bioscaffold

Cai, Zizhen; Liu, Zehua; Hu, Xiaodong; Kuang, Hekun; Zhai, Jinsong

doi:10.1007/s42242-019-00054-7

Cited by 60 publications

(19 citation statements)

References 11 publications

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“…Mechanical properties are critical evaluation indices for the structure used in orthopedic implants (Wang et al, 2016;Zhang et al, 2018;Cai et al, 2019). The porous structure of the implant can produce a good biological reaction with the host bone in vivo and solve the problem of stress shielding only when its mechanical properties meet certain conditions.…”

Section: Analysis Of Compression Test Resultsmentioning

confidence: 99%

Analysis of Mechanical Properties and Permeability of Trabecular-Like Porous Scaffold by Additive Manufacturing

Chao¹,

Jiao²,

Liang³

et al. 2021

Front. Bioeng. Biotechnol.

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Human bone cells live in a complex environment, and the biomimetic design of porous structures attached to implants is in high demand. Porous structures based on Voronoi tessellation with biomimetic potential are gradually used in bone repair scaffolds. In this study, the mechanical properties and permeability of trabecular-like porous scaffolds with different porosity levels and average apertures were analyzed. The mechanical properties of bone-implant scaffolds were evaluated using finite element analysis and a mechanical compression experiment, and the permeability was studied by computational fluid dynamics. Finally, the attachment of cells was observed by confocal fluorescence microscope. The results show that the performance of porous structures can be controlled by the initial design of the microstructure and tissue morphology. A good structural design can accurately match the performance of the natural bone. The study of mechanical properties and permeability of the porous structure can help address several problems, including stress shielding and bone ingrowth in existing biomimetic bone structures, and will also promotes cell adhesion, migration, and eventual new bone attachment.

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Section: Analysis Of Compression Test Resultsmentioning

confidence: 99%

Analysis of Mechanical Properties and Permeability of Trabecular-Like Porous Scaffold by Additive Manufacturing

Chao¹,

Jiao²,

Liang³

et al. 2021

Front. Bioeng. Biotechnol.

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“…The Gibson-Ashby power law, commonly used as an empirical model for describing the relationship between modulus and density of lattice structures, is employed to study the effects of relative density. [33][34][35][36] The power law is expressed as E ¼ C r n where C and n are coefficients depending on the lattice types and our results are fitted to the expression under fixed C = 1 to satisfy % E = 1 when r = 1, i.e., only one fitting parameter n is used. From our simulation results, the maximum Young's modulus curve is obtained which is found to be accurate in the entire range of the relative density.…”

Section: Resultsmentioning

confidence: 99%

Generative machine learning algorithm for lattice structures with superior mechanical properties

Lee

Zhang

2022

Mater. Horiz.

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“…The results illustrated that Gyroid skeletal-TPMS had the most flexible design space, that is, it performed well in three aspects (Barba et al, 2019). However, the compressive strength of sheet-TPMS was 1.3-2 times that of skeleton TPMS, and its toughness was also higher (Cai et al, 2019).…”

Section: Tpmsmentioning

confidence: 93%

Porous Scaffold Design for Additive Manufacturing in Orthopedics: A Review

Chen

Han

Wang

et al. 2020

Front. Bioeng. Biotechnol.

154

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With the increasing application of orthopedic scaffolds, a dramatically increasing number of requirements for scaffolds are precise. The porous structure has been a fundamental design in the bone tissue engineering or orthopedic clinics because of its low Young's modulus, high compressive strength, and abundant cell accommodation space. The porous structure manufactured by additive manufacturing (AM) technology has controllable pore size, pore shape, and porosity. The single unit can be designed and arrayed with AM, which brings controllable pore characteristics and mechanical properties. This paper presents the current status of porous designs in AM technology. The porous structures are stated from the cellular structure and the whole structure. In the aspect of the cellular structure, non-parametric design and parametric design are discussed here according to whether the algorithm generates the structure or not. The non-parametric design comprises the diamond, the body-centered cubic, and the polyhedral structure, etc. The Voronoi, the Triply Periodic Minimal Surface, and other parametric designs are mainly discussed in parametric design. In the discussion of cellular structures, we emphasize the design, and the resulting biomechanical and biological effects caused by designs. In the aspect of the whole structure, the recent experimental researches are reviewed on uniform design, layered gradient design, and layered gradient design based on topological optimization, etc. These parts are summarized because of the development of technology and the demand for mechanics or bone growth. Finally, the challenges faced by the porous designs and prospects of porous structure in orthopedics are proposed in this paper.

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The effect of porosity on the mechanical properties of 3D-printed triply periodic minimal surface (TPMS) bioscaffold

Cited by 60 publications

References 11 publications

Analysis of Mechanical Properties and Permeability of Trabecular-Like Porous Scaffold by Additive Manufacturing

Analysis of Mechanical Properties and Permeability of Trabecular-Like Porous Scaffold by Additive Manufacturing

Generative machine learning algorithm for lattice structures with superior mechanical properties

Porous Scaffold Design for Additive Manufacturing in Orthopedics: A Review

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