“…[54][55][56] Ice is frequently used in dental practice to dull the pain of needle insertion into mucosa. 55,57 In the mucosa of the palate, ice provided more effective pain reduction, decreased application time requirement, greater ease of application, and avoidance of displeasing taste when compared with eutectic mixture of local anesthetic creams. 57 The results of a study comparing the efficacy of eutectic mixture of local anesthetic topical anesthesia and the application of ice before cutaneous needle insertion showed that the eutectic mixture of local anesthetic provided better pain control but was hindered by the slow onset, whereas ice was inexpensive, fast-acting, and readily available, and still produced statistically significant pain reduction.…”