The Effect of Prostaglandin E1 on Patients of Lumbar Canal Stenosis.

Abstract

We treated 10 patients of lumbar spinal canal stenosis with intravenous drip of Prostaglandin E1. Doses were 120pg/day or 60 ,ug/day during a week. Four cases were very good and 4 cases were good on satisfaction of patients. The test of spinal evoked potential was done on 7 cases. We recorded at rest and after load of gait, and compared the prolongation of latency and the decline of amplitude between pre and post-treatment. After treatment, the prolongation of latency by load of gait decreased in comparison with that of pre-treatment. The continuity of effect existed on 4 cases 1 month after treatment. Side effects were vasculitis in 5 cases and the worse of gastric ulcer in 1 case.

Prostaglandin E1 Treatment for Lumbar Spinal Canal Stenosis: Review of the Literature

“…A literature search found 10 studies that reported clinical outcomes of PGE 1 treatment for LSCS (Table ) . Takakura et al .…”