Sleep of patients with pruritus deteriorate due to the symptoms of pruritus. In this study, it was aimed to assess the sleep quality of dermatology patients with complaints of pruritus. This case-control study was conducted between August 2017 and December 2017. The study population consisted of 100 patients with pruritus and 100 patients without pruritus who presented to the dermatology outpatient clinic of Private Salihli Hospital, a private hospital in Manisa, a province in Turkey. The study data were collected the "Sociodemographic Characteristics Questionnaire", "Pittsburgh Sleep Quality Index (PSQI)" and "Insomnia Severity Index (ISI)". The SPSS 15 was used for the analysis of the data. The mean age of the participants was 37.16 ± 14.33. While of the participants in the experimental group, 69% were female and 49% were married, of the participants in the control group, 81% were female and 54% were married. Of the participants, 75.0% in the experimental group and 57% in the control group had poor sleep quality. It was determined that sleep quality was significantly lower in the experimental group than that in the control group.