The effect of quitting smoking on the risk of unfavorable events after surgical treatment of oral potentially malignant lesions

Vladimirov, Boyan; Schiødt, Morten

doi:10.1016/j.ijom.2009.06.026

Cited by 33 publications

(11 citation statements)

References 25 publications

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“…Cessation of smoking habits considerably reduces the risk of developing cancer after surgical treatment of oral potentially malignant lesions (17). …”

Section: Leukoplakia and Erythroplakiamentioning

confidence: 99%

Oral potentially malignant disorders: Is malignant transformation predictable and preventable?

Waal

2014

Med Oral

148

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Leukoplakia is the most common potentially malignant disorder of the oral mucosa. The prevalence is approximately 1% while the annual malignant transformation ranges from 2% to 3%. At present, there are no reliable clinicopathological or molecular predicting factors of malignant transformation that can be used in an individual patient and such event can not truly be prevented. Furthermore, follow-up programs are of questionable value in this respect. Cessation of smoking habits may result in regression or even disappearance of the leukoplakia and will diminish the risk of cancer development either at the site of the leukoplakia or elsewhere in the mouth or the upper aerodigestive tract. The debate on the allegedly potentially malignant character of oral lichen planus is going on already for several decades. At present, there is a tendency to accept its potentially malignant behaviour, the annual malignant transformation rate amounting less than 0.5%. As in leukoplakia, there are no reliable predicting factors of malignant transformation that can be used in an individual patient and such event can not truly be prevented either. Follow-up visits, e.g twice a year, may be of some value. It is probably beyond the scope of most dentists to manage patients with these lesions in their own office. Timely referral to a specialist seems most appropriate, indeed. Key words:Oral potentially malignant disorders, oral leukoplakia, oral lichen planus.

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“…Cessation of smoking habits considerably reduces the risk of developing cancer after surgical treatment of oral potentially malignant lesions (17). …”

Section: Leukoplakia and Erythroplakiamentioning

confidence: 99%

Oral potentially malignant disorders: Is malignant transformation predictable and preventable?

Waal

2014

Med Oral

148

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“…Evidence that serial biopsies or regular follow-up ultimately improves the clinical outcome of patients is lacking; however, there is evidence that risk factor avoidance may influence patient outcome. Fifty-one smokers with leukoplakia/erythroplakia who underwent surgical treatment then received advice regarding smoking cessation [13]. Sixteen patients stopped smoking, with only one of these patients developing a recurrence, and none developed new lesions or cancers.…”

Section: Conservative or Active Surveillancementioning

confidence: 99%

Oral Dysplasia: Biomarkers, Treatment, and Follow-up

Nankivell

Mehanna

2011

Curr Oncol Rep

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Dysplasia affecting the oral mucosa has a malignant potential. The options for treatment of oral dysplasia are limited. Surgery remains the mainstay of management, with no strong evidence for medical treatments currently available. Histological grading alone does not accurately predict which dysplastic lesions will progress to cancer, which poses the clinician with difficult decisions regarding the most appropriate treatment and may lead to some patients being overtreated, with potentially unnecessary morbidity. The use of biomarkers may help to improve prediction of which cases are likely to transform. The efficacy of individual markers for prediction will be discussed in this paper. There is also a lack of consensus on the optimal frequency and duration of follow-up for patients with oral dysplasia.

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“…Continued tobacco use reduces the effectiveness of radiotherapy, exacerbates or prolongs complications secondary to treatment of head and neck cancer such as mucositis and xerostomia, and compromises pulmonary function. 3,20…”

Section: Discussionmentioning

confidence: 99%

Severe Radiodermatitis and Risk Factors Associated in Head and Neck Cancer Patients

Cardozo

Simões

Santos

et al. 2020

Texto contexto - enferm.

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Objective: To evaluate the association between sociodemographic, clinical, and treatment factors in the outcome of severe radiodermatitis in patients with head and neck cancer seen at the nursing consultation; and to analyze the impact of severe radiodermatitis cases on therapeutic follow-up. Method: A quantitative, documentary research conducted with medical records of 167 patients with head and neck cancer submitted to radiotherapy with curative indication followed in the nursing consultation in 2016. A structured form was used for data collection and analytical and descriptive statistics were used for its analysis. Results: Of the 99.4% patients who had radiodermatitis, 11.4% were severe cases. Severe radiodermatitis was associated with the type of equipment, treatment technique and presence of comorbidities. Of the patients who presented grade three, 53% had temporary discontinuation of treatment. Conclusion: Head and neck cancer patients who undergo radiotherapy with curative indication are at risk for severe radiodermatitis. Nursing consultation is important to minimize the severity of this event and the reduction of temporary treatment interruption due to this adverse reaction.

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The effect of quitting smoking on the risk of unfavorable events after surgical treatment of oral potentially malignant lesions

Cited by 33 publications

References 25 publications

Oral potentially malignant disorders: Is malignant transformation predictable and preventable?

Oral potentially malignant disorders: Is malignant transformation predictable and preventable?

Oral Dysplasia: Biomarkers, Treatment, and Follow-up

Severe Radiodermatitis and Risk Factors Associated in Head and Neck Cancer Patients

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