The Effect of Recorded Mum's Lullaby and Brahm’s Lullaby on Oxygen Saturation in Preterm Infants: a Randomized Double-Blind Clinical Trial

Abstract

Introduction: Music stimulation has been shown to provide significant benefits to preterm infants. Thus the aim of this study was determine the effect of recorded mum's lullaby and Brahm’s lullaby on oxygen saturation in preterm infants. Methods: This double-blind randomized controlled trial was carried out on 66 premature newborns with the postnatal age of ≥3 days and weight ≤ 2800 grams at Taleghani Hospital. Infants were randomly divided into three groups: control, Brahm’s lullaby and Mum's lullaby groups. Infants were continuously monitored for primary outcome of percutaneous oxygen saturation, for three consecutive sessions. Results: There were significant difference in neonate oxygen saturation between the Brahm’s lullaby and Mum's lullaby as compared with control groups in the 15 minutes after intervention. Conclusion: This study showed beneficial effects of Brahm’s lullaby and Mum's lullaby sound. Therefore; it may be used for improving short term outcomes in premature infants.

Do Hospitalized Premature Infants Benefit from Music Interventions? A Systematic Review of Randomized Controlled Trials

“…The total number of subjects was 1128, all born prematurely before 37 weeks, admitted to a NICU and receiving music interventions at ages ranging from 25 to 40 weeks GA. The studies dated from 2003 to 2016 and had been carried out in the USA [ 4 , 12 , 23 – 26 ], Israel [ 27 – 29 ], Iran [ 30 – 33 ], Turkey [ 34 ], Australia [ 35 , 36 ], Lithuania [ 37 ], Germany [ 38 , 39 ] and Brazil [ 40 ]. Live music was offered in four studies; recorded music in eighteen studies.…”

Preterm infant physiological responses to music therapy: a systematic review

“…In two studies, the music was delivered using headphones, 11,12 eleven studies used speakers or MP3 players inside or close to the incubator; one study used PAL, 13 two studies did not clearly state the delivery mode used. 18,19 The decibel levels were set between 45-76 dB. The intervention was offered 1-3 times daily for 10-60 minutes, and given for 1 to 8 days.…”

“…Music therapy began 30-60 minutes after feeding, nursing, as well as during or after heel stick procedures, at 9-10 AM, 10 AM -7 PM, 2-3 PM, 8-9 PM, 9-10 PM, or either morning or afternoon. [11][12][13][14][18][19][20][21][22][23][24][25][26][27] Three studies used recorded maternal voice reading a book or singing a song. The recordings were delivered using a tape player or speaker placed inside the incubator, except for one study that did not explain the music delivery method.…”

“…The recordings were delivered using a tape player or speaker placed inside the incubator, except for one study that did not explain the music delivery method. 19 Sound intensity was set within the range of 55-70 dB. The intervention was given for 10-15 minutes, 1-3 times daily, for 2, 3, or 14 consecutive days.…”

“…Music therapy was shown to significantly decrease the heart rate 12,14,17,18,20,23,26,27 and respiratory rate, 13,18,22,23,26,27 and increase oxygen saturation. 12,19,20,22 Participants in all studies started from 28 weeks' gestational age. According to fetal auditory development, myelination occurs at the 27 th week of gestation, from the cochlea to the auditory thalamus, 29 and external auditory input begins to reorganize the auditory cortex.…”