The effect of rutin in experimental malignant hypertension

Hellerstein, Herman K.; Orbison, J. Lowell; Rodbard, Simon; Wilburne, Morris; Katz, Louis N.

doi:10.1016/0002-8703(51)90245-1

Cited by 23 publications

(12 citation statements)

References 11 publications

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“…Some compounds from asparagus such as flavonoids, phenolic acids, and saponins have been reported to show biological and pharmacological activities (Deschner et al, 1991;Hartung et al, 1990;Wang et al, 2003). Rutin is one of the major flavonoids present in asparagus (Chin et al, 2002;Deeds and Couch, 1948;Maeda et al, 2005) and has been reported to exert biological effects such as suppressing the weakening of capillaries associated with hemorrhagic disease (Griffith et al, 1944) and reducing hypertension in humans (Hellerstein et al, 1951). The anthocyanins, caffeic acid, and other phenolic compounds from asparagus were also reported to show biological and/or pharmacological activities (Vinson et al, 1995;Yamanaka et al, 1997).…”

Section: Introductionmentioning

confidence: 99%

Light Condition Influences Rutin and Polyphenol Contents in Asparagus Spears in the Mother-fern Culture System during the Summer–Autumn Harvest

Maeda

Honda

Sonoda

et al. 2010

J. Japan. Soc. Hort. Sci.

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We investigated the variation in rutin and total polyphenol contents in asparagus spears under different conditions of mother-fern culture. Rutin and polyphenol contents were highest at early spring harvest at all test sites. The contents gradually decreased during the harvest season. In particular, a considerable decrease was observed after the growth of mother ferns. The absorption of the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical was weaker in summer. Rutin content in the spears of plants grown outdoors was generally higher than in these grown in a greenhouse, except at early spring harvest. Rutin contents decreased in the spears of plants grown under a shading net or an ultraviolet (UV) radiation-filtering film. These results suggest that cultivation conditions, especially light conditions, have a great influence on rutin and polyphenol contents. We evaluated two new methods to increase rutin content by improving light conditions. Light conditions in asparagus rows were improved by using light-reflecting sheets and net screens; however, a significant increase in rutin content was observed only when net screening was used, implying that this method is better than light reflecting sheets to increase the rutin content.

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Section: Introductionmentioning

confidence: 99%

Light Condition Influences Rutin and Polyphenol Contents in Asparagus Spears in the Mother-fern Culture System during the Summer–Autumn Harvest

Maeda

Honda

Sonoda

et al. 2010

J. Japan. Soc. Hort. Sci.

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“…Asparagus spears are known to contain a large amount of rutin (RT), [1][2][3][4] which has been found to possess antiinflammatory, anti-tumor, and anti-bacterial/viral properties 5,6) along with potent radical-scavenging activity, as well as protective effects in protecting against capillary fragility and arteriosclerotic vascular changes. 7) Previous studies have found that asparagus contains 30-70 mg/100 g FW of RT, a level similar to that of buckwheat, 2,3) 75% of the anti-oxidative capacity of asparagus can be attributed to RT, 4) and protodioscin (PD), an anti-tumor substance, is present in the bottoms of spears, 1,8,9) suggesting the potential of asparagus as a functional food that can be utilized effectively.…”

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confidence: 99%

Effects of Various Asparagus Production Methods on Rutin and Protodioscin Contents in Spears and Cladophylls

Motoki¹,

Kitazawa²,

Maeda³

et al. 2012

Bioscience, Biotechnology, and Biochemistry

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“…Rutin (RU), a flavonoid glycoside compound exhibits broad range of physiological activities such as anti‐oxidant 23a, antiviral 23b, anti‐inflammatory 23c, and anti‐depression 23d. It has potential to treat diabetes 24a and hypertension 24b. RU has a direct construction action on the capillary bed and decreases the permeability and fragility of the blood vessels 25.…”

Section: Introductionmentioning

confidence: 99%

Nanocrystalline Metallosilicate Modified Electrodes for the Simultaneous, Sensitive, and Selective Determination of Riboflavin, Rutin, and Pyridoxine

Kaur

Srivastava

2014

Electroanalysis

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Nanocrystalline metallosilicate modified glassy carbon electrodes were fabricated for the simultaneous determination of vitamins. Among these, nanocrystalline zirconosilicate exhibited the highest activity with a linear range from 30 nM-500 mM for riboflavin and 120 nM-600 mM for rutin and pyridoxine. Sensitivity values of 2.8, 1.49, and 1.13 mA/mM cm 2 and lower detection limits of 5 nM, 30 nM, and 30 nM for riboflavin, rutin, and pyridoxine, respectively, were found. The proposed sensor is stable and reproducible (RSD < 3.5 %). The analytical performance of this sensor was demonstrated in the pharmaceutical preparations (multivitamin tablets) with satisfactory recovery (97-103 %).

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The effect of rutin in experimental malignant hypertension

Cited by 23 publications

References 11 publications

Light Condition Influences Rutin and Polyphenol Contents in Asparagus Spears in the Mother-fern Culture System during the Summer–Autumn Harvest

Light Condition Influences Rutin and Polyphenol Contents in Asparagus Spears in the Mother-fern Culture System during the Summer–Autumn Harvest

Effects of Various Asparagus Production Methods on Rutin and Protodioscin Contents in Spears and Cladophylls

Nanocrystalline Metallosilicate Modified Electrodes for the Simultaneous, Sensitive, and Selective Determination of Riboflavin, Rutin, and Pyridoxine

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