The effect of rutin on experimentally induced acute heart contusion in rats. Biochemical and histopathological evaluation

Elma, Bekir

doi:10.14744/tjtes.2021.97760

Cited by 6 publications

(3 citation statements)

References 48 publications

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“…Also, they reported on the cardioprotective mechanisms of RTN, particularly in cardiac hypertrophy. On the other hand, treated with RTN caused inhibiting the apoptosis of cardiomyocytes and improving cardiac function and related to the restoration of the structure and function of myocardial mitochondria [1], reduce cardiomyocyte damage [34], and it may be protecting cardiac tissue from oxidative damage due to the anti-inflammatory effect associated with the inhibition of interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) [14].…”

Section: Discussionmentioning

confidence: 99%

Cardioprotective Effects of Rutin and Mesenchymal Stem Cells on Acetaminophen Induced Cardiac Enzymatic Damage in Rats

Elduob,

Alshailabi,

Efkeren

2024

Glj

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The aims of study to determine the cardioprotective effects of rutin and mesenchymal stem cells on acetaminophen induced cardiac enzymatic damage in rats. seventy male rats were divided into two studies. One: twenty young male rats were used as a source of bone marrow-derived MSCs. Two: fifty adult male rats were divided into five groups: G1: control group; G2: rats were given of PARA (750 mg/kg b.w.) every 72h orally for 21 days, then left for 30 and 60 days without any treatment; G3: rats were given of PARA then, administrated of rutin (25mg/kg b.w/d) for 30 and 60 days; G4: rats were given of PARA then, injected by BM-MSCs (1.5x 106 cells in 0.5 PBS) in the tail vein for 30 and 60 days, and G5: rats were given of PARA then, injected by BM-MSCs in the tail vein, and then administrated of rutin orally for 30 and 60 days. Treated by the PARA showed, a significant increased the CK-MB and LDH levels when compared with normal rats at 30 and 60 days. While, the PARA+MSCs+RTN group showed, a significant decrease in the CK-MB and LDH levels as compared with other groups rats at 30 and 60 days. Rats treated with both MSCs and RTN after treated by PARA showed, a markedly improved in cardiac enzymes activity.

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Section: Discussionmentioning

confidence: 99%

Cardioprotective Effects of Rutin and Mesenchymal Stem Cells on Acetaminophen Induced Cardiac Enzymatic Damage in Rats

Elduob,

Alshailabi,

Efkeren

2024

Glj

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“…These results were confirmed by previous studies that showed that treatment with rutin in tissues can prevent and inhibit lung infections. a study of Elma et al (2022) explained the effect of rutin on blunt trauma pulmonary contusion in mice and how it reduced and improved the effects on lung tissue and contributed to its treatment.…”

Section: Histological Studymentioning

confidence: 99%

Full Text Book of Minar Congress9

2023

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Using geogrid in road pavements can enhance pavement performance by enhancing bearing capacity, lateral confinement, and overall stiffness, in addition to lowering lateral and vertical pavement deformations. A Number of large-scale direct shear experiments were applied in this paper to assess the influence of compaction degree on the mechanical interaction among a clay subgrade soil and a subbase layer in both cases of using and not using reinforcement at the interface. Clay subgrade soil, Subbase granular materials as Type B, and Biaxial Geogrid BX1100 were employed as reinforcing materials in this investigation. In the current investigation, direct shear test was employed by fabricating a large-scale direct shear apparatus consisting of a square upper box with dimensions of (200 mm × 200 mm × 100 mm), and a rectangular lower box with dimensions of (200 mm × 250 mm × 100 mm). On specimens with and without reinforcement, 40 interface tests were performed for five degrees of compaction (100, 98, 93, 90, and 84%), which corresponded to (60, 55, 50, 45, and 40 blows/layer) for the shear box, with the regular loads applied for each combination being (25 -50 -75 -100) kPa. The results demonstrate that the interface shear stress curves grew and trailed a similar pattern for the four normal stress (25 -50 -75 -100) kPa. At their optimal moisture levels, the effect of dry density on the interface properties of these combinations (geogrid-soil) was also examined. The interface shear failure envelopes grew with increasing molding dry densities (i.e. degree of compaction), reaching a maximum value at 97% degree of compaction.

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Section: Histological Studymentioning

confidence: 99%

Inhibitory Effect and Antioxidant Activity of the Internal Membrane Decomposition of Egg Shells

Fadhel Abbas

2023

Full Text Book of Minar Congress9

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Different samples were collected from the internal membrane of the white and red eggshells local and imported to prepare protein hydrolyases using the enzyme Flavourzyme and studied the chemical composition of the raw material used moisture, ash, protein and fats where the proportions of chemical content were comparable to the samples prepared for the different species of hen and age, The decomposition lasted for two hours during which the degree of decomposition was estimated every half on hour. The hydrolyses of the internal membranes of the imported red egg shells were 0.5990%, the hydrolysates showed the highest reductive strength of the imported white eggs, 9.899%, while the protein decomposition of the eggshells of the eggshells in relation to the feasibility of ferrous ion binding of local red eggs was 40.547. Acquisition of hydrogen peroxide showed that the hydrolysates prepared from the internal membranes of locally red eggs and imported red eggs was a close result, reaching 333.92, whereas the ability of the hydroxyl root to decompose was the protein decomposition of the internal membranes of the shells of flat white eggs. 21.433% and Degradable internal membranes of eggs imported white super Oxide ability to seize the radichal of the highest negative value of the samples prepared 27.061% while did not appear to Tallit Albrootinh for all kinds of internal membranes effective inhibitory to bacteria.

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The effect of rutin on experimentally induced acute heart contusion in rats. Biochemical and histopathological evaluation

Cited by 6 publications

References 48 publications

Cardioprotective Effects of Rutin and Mesenchymal Stem Cells on Acetaminophen Induced Cardiac Enzymatic Damage in Rats

Cardioprotective Effects of Rutin and Mesenchymal Stem Cells on Acetaminophen Induced Cardiac Enzymatic Damage in Rats

Full Text Book of Minar Congress9

Inhibitory Effect and Antioxidant Activity of the Internal Membrane Decomposition of Egg Shells

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