The Effect of Scaling and Root Planing on Glycaemic Control, Periodontal Status and Gingival Crevicular f luid TN f - α Levels in an Indian Population- To Reveal the Ambivalent Link

The relationship between leptin and periodontitis: a literature review

“…However, a 2017 meta-analysis found that serum leptin levels in systemically healthy periodontitis patients did not change after periodontal treatment ( Zhu et al, 2017 ). The inconsistency in these studies’ results may be attributed to the fact that serum leptin levels are affected not only by the condition of periodontal tissues but also by an individual’s other body tissues, health status, lifestyle, age, and so on Soorya et al (2014) . However, the underlying mechanisms of these additional factors are unclear and should be clarified further.…”

Dipeptidyl‐peptidases: Key enzymes producing entry forms of extracellular proteins in asaccharolytic periodontopathic bacterium Porphyromonas gingivalis

“…Currently, the two-way relationship between periodontal disease and type 2 diabetes mellitus is accounted for by chronic inflammation, in which an elevated level of tumor necrosis factor-α derived from the liver by lipopolysaccharide of periodontopathic Gramnegative bacteria, results in insulin resistance (Soorya et al, 2014;Takano et al, 2010;Teeuw et al, 2010). We recently proposed that an additional and direct link exists between the two diseases, in which periodontopathic bacterial DPP4 degrades incretins (Ohara-Nemoto et al, 2017).…”