In this research, a meta-analysis was conducted to find out the effect level of STEM education on students' academic achievement in science courses. Scientific studies which were conducted and published in Turkey between January 2018 and March 2020 were reviewed in the research. As a result of the literature review, 54 studies that were suitable for the purpose of the study were reached. In analyses conducted with a statistical analysis program, effect levels were compared in terms of subject area and number of participants in addition to approaches/method used. According to the results of this research, it was concluded that STEM education was more effective in increasing students' achievement in science courses when compared with teacher-centred teaching methods. According to the results examined according to other variables discussed in the research, significant difference was found in terms of the year in which the study was conducted, the researcher's job, application period of the study and the number of participants. According to the results of the examined variables, the largest effect size was found in the field of biology, at high school level, doctoral publications, in researchers who were teachers, with 81 and above participants, in studies conducted in 2019.