2002
DOI: 10.1592/phco.22.13.1084.33514
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The Effect of Sepsis During Parenteral Nutrition on Hepatic Microsomal Function in Rats

Abstract: Hepatic CYP concentration declines with PN and is further decreased when compounded by sepsis. The disproportional decrease in ECOD activity relative to CYP concentration with PN is unchanged by sepsis, indicating a selective alteration in hepatic isoenzymes by PN.

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