The effect of sevoflurane compared to propofol maintenance on post-surgical quality of recovery in patients undergoing an ambulatory gynecological surgery: A prospective, randomized, double-blinded, controlled, clinical trial

Oliveira, Gildàsio S. De; Bialek, Jane M.; Rodes, Meghan Elizabeth; Kendall, Mark C.; McCarthy, Robert J.

doi:10.1016/j.jclinane.2017.10.001

Cited by 30 publications

(25 citation statements)

References 24 publications

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“…However, some recent studies reported no difference in the effects of propofol and sevo urane on postoperative recovery outcomes, namely the QoR-40 scores, postoperative pain, length of PACU stay, and complications including PONV (34)(35)(36). Possible explanations for this discrepancy between our results and those of previous studies include different study population characteristics, surgical aetiologies and analgesic regimens.…”

Section: Discussioncontrasting

confidence: 99%

Comparison of the Impact of Propofol and Sevoflurane on Early Postoperative Recovery in Living Donors After Laparoscopic Donor Nephrectomy: A Prospective Randomized Controlled Study

Han

Park

Hong

et al. 2020

Preprint

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Background: Enhancing postoperative recovery of the donor is important to encourage living kidney donation. We investigated the effects of anesthetic agents (intravenous [IV] propofol versus inhaled [IH] sevoflurane) on the quality of early recovery of healthy living kidney donors after hand-assisted laparoscopic nephrectomy (HALN) under analgesic intrathecal morphine injection. Methods: This single-center, prospective randomized controlled study enrolled 80 living donors undergoing HALN from October 2019 to June 2020 at Seoul St. Mary’s hospital. Donors were randomly assigned to the IV propofol group or IH sevoflurane group. To measure the quality of recovery, we used the Korean version of the Quality of Recovery-40 questionnaire (QoR-40K) on postoperative day (POD) 1, and ambulation (success rate, number of footsteps) 6–12 hours after surgery and on POD 1. The pain score for the wound site, IV opioid requirement, postoperative complications including incidence of nausea/vomiting, length of in-hospital stay were also assessed.Results: The global QoR-40K score and all subscale scores (physical comfort, emotional state, physical independence, psychological support, and pain) were significantly higher in the IV propofol group than in the IH sevoflurane group. The numbers of footsteps at all timepoints were also higher in the IV propofol group. The donors in the IV propofol group had a lower incidence of nausea/vomiting, and a shorter hospitalization period.Conclusions: Total IV anesthesia with propofol led to better early postoperative recovery than that associated with IH sevoflurane.Trial registration: Clinical Research Information Service, Republic of Korea (approval number: KCT0004351) on October 18, 2019.https://cris.nih.go.kr/cris/search/search_result_st01_kren.jsp?seq=15768&sLeft=2&ltype=my&rtype=my

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Section: Discussioncontrasting

confidence: 99%

Comparison of the Impact of Propofol and Sevoflurane on Early Postoperative Recovery in Living Donors After Laparoscopic Donor Nephrectomy: A Prospective Randomized Controlled Study

Han

Park

Hong

et al. 2020

Preprint

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“…However, some recent studies have reported no differences in the effects of propofol and sevo urane on postoperative recovery outcomes, namely the QoR-40 scores, postoperative pain, length of PACU stay, and complications, including PONV (37)(38)(39). Possible explanations for this discrepancy between our results and those of previous studies include different study population characteristics, surgical etiologies and analgesic regimens.…”

Section: Discussioncontrasting

confidence: 99%

“…Speci cally, the global QoR-40K score was 169 (162-179) in the IV propofol group and 142 (131-154) in the IH sevo urane group. Sub-dimension scores in the IV propofol group were 51 (47-54) for physical comfort, 41 (38)(39)(40)(41)(42)(43) for emotional state, 32 (29)(30)(31)(32)(33)(34)(35) for psychological support, 17 (13)(14)(15)(16)(17)(18)(19)(20) for physical independence and 31 (28)(29)(30)(31)(32)(33) for pain while these scores in the IH sevo urane group were 44 (38- The success rate of early ambulation was marginally higher in the IV propofol group (40 [100%] in the IV propofol group vs. 35 [87.5%] in the IH sevo urane group; p=0.055); however, all of the donors could ambulate on POD 1 ( Table 3). The numbers of steps during the early and late postoperative periods, and the total steps on POD 1, were signi cantly higher in the IV propofol group than in the IH sevo urane group.…”

Section: Qor-40k Scores and Ambulationmentioning

confidence: 99%

Comparison of the impact of propofol versus sevoflurane on early postoperative recovery in living donors after laparoscopic donor nephrectomy: a prospective randomized controlled study

Han

Park

Hong

et al. 2020

Preprint

View full text Add to dashboard Cite

Background: Enhancing postoperative recovery of the donor is important to encourage living kidney donation. We investigated the effects of anesthetic agents (intravenous [IV] propofol versus inhaled [IH] sevoflurane) on the quality of early recovery of healthy living kidney donors after hand-assisted laparoscopic nephrectomy (HALN) under analgesic intrathecal morphine injection. Methods: This single-center, prospective randomized controlled study enrolled 80 living donors undergoing HALN from October 2019 to June 2020 at Seoul St. Mary’s Hospital. Donors were randomly assigned to the IV propofol group or IH sevoflurane group. To measure the quality of recovery, we used the Korean version of the Quality of Recovery-40 questionnaire (QoR-40K) on postoperative day (POD) 1, and ambulation (success rate, number of footsteps) 6–12 hours after surgery and on POD 1. The pain score for the wound site, IV opioid requirement, postoperative complications including incidences of nausea/vomiting, and length of in-hospital stay were also assessed.Results: The global QoR-40K score and all subscale scores (physical comfort, emotional state, physical independence, psychological support, and pain) were significantly higher in the IV propofol group than in the IH sevoflurane group. The numbers of footsteps at all time points were also higher in the IV propofol group. Donors in the IV propofol group had a lower incidence of nausea/vomiting, and a shorter hospitalization period.Conclusions: Total IV anesthesia with propofol led to better early postoperative recovery than that associated with IH sevoflurane.

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“…The variables obtained from trials included the sample size, local anesthetic type and dose, type of surgery, number of participants in treatment groups, 24, 48, and 72 hours postoperative pain scores, 24, 48, and 72 hours postoperative opioid consumption, postoperative nausea and vomiting, and length of hospital stay (hours). Postoperative opioid consumption was converted to the mg equivalents dose of oral morphine assuming no cross-tolerance (morEq) [ 23 , 24 ]. Visual analog scale or numeric rating scale of pain was converted to a 0-10 Numeric Rating Scale (0 = no pain, 10 = extreme pain).…”

Section: Methodsmentioning

confidence: 99%

Liposome Bupivacaine Compared to Plain Local Anesthetics to Reduce Postsurgical Pain: An Updated Meta-Analysis of Randomized Controlled Trials

Kendall

Alves

Oliveira

2018

Pain Research and Treatment

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Objective Peripheral nerve blocks for postoperative analgesia have improved block success, but analgesia efficacy has been limited by the short duration of traditional local anesthetics. The results of randomized trials comparing liposome bupivacaine with conventional local anesthetic formulations (e.g., plain bupivacaine and ropivacaine) have generated conflicting results. This study was conducted to systematically review the effectiveness of analgesic efficacy of liposome bupivacaine infiltration at the surgical site versus plain local anesthetic bupivacaine or ropivacaine in patients undergoing surgery. Methods PRISMA statement guidelines were followed. A search of electronic databases National Library of Medicine's PubMed database, Cochrane Database of Systematic Reviews, Embase, and Google Scholar from January 2012 to September 2017 was performed. Among the 1,612 records identified, 9 randomized controlled trials involving 779 patients were eligible for data extraction and meta-analysis. Results Liposome bupivacaine did not reduce postsurgical pain at rest compared to plain local anesthetics at 24 and 48 hours after surgery. Moreover, liposome bupivacaine did not reduce postoperative opioid consumption at 24, 48, or 72 hours when compared to plain local anesthetics. Liposome bupivacaine did reduce postoperative nausea when compared to plain local anesthetics (P =<0.3). There was no significant difference in hospital length of stay between study groups, the use of plain bupivacaine or ropivacaine, or among orthopedic or nonorthopedic procedures. No manifestations of local anesthetic toxicity were reported. Conclusions Our results suggest that liposome bupivacaine does not have an analgesic advantage when compared to plain local anesthetics at the surgical site for patients undergoing surgical procedures.

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The effect of sevoflurane compared to propofol maintenance on post-surgical quality of recovery in patients undergoing an ambulatory gynecological surgery: A prospective, randomized, double-blinded, controlled, clinical trial

Cited by 30 publications

References 24 publications

Comparison of the Impact of Propofol and Sevoflurane on Early Postoperative Recovery in Living Donors After Laparoscopic Donor Nephrectomy: A Prospective Randomized Controlled Study

Comparison of the Impact of Propofol and Sevoflurane on Early Postoperative Recovery in Living Donors After Laparoscopic Donor Nephrectomy: A Prospective Randomized Controlled Study

Comparison of the impact of propofol versus sevoflurane on early postoperative recovery in living donors after laparoscopic donor nephrectomy: a prospective randomized controlled study

Liposome Bupivacaine Compared to Plain Local Anesthetics to Reduce Postsurgical Pain: An Updated Meta-Analysis of Randomized Controlled Trials

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