The main task of agriculture is to increase the productivity of cultivated plants, and therefore the development of methods that regulate the growth and development of agricultural crops is becoming increasingly important. It is known that plant development in response to external stimuli is regulated by peptide phytohormones. In addition, peptides are considered as antimicrobial agents. The review examines peptides of the CLE, EPF, PSY, PSK, RGF, CIF families, dipeptide KE, tripeptide EDR and tetrapeptides AEDL, KEDG, AEDR, KEDP and their role in the regulation of plant differentiation and growth. The wide range of biological activity of peptides allows us to propose their use to increase the productivity of new generation plants.