The effect of six months of elastic band resistance training, nutritional supplementation or cognitive training on chromosomal damage in institutionalized elderly

Circulating cell-free DNA, telomere length and bilirubin in the Vienna Active Ageing Study: exploratory analysis of a randomized, controlled trial

“…Some evidence suggests that in a case of folate deprivation NBuds might contain a larger amount of telomeric DNA, leading to an abnormal increase in telomeric content31. The present study participants indeed had an inadequate baseline level of folate28 in erythrocytes, which might partly explain our results.…”

“…Briefly, functional parameters have been found to improve over time and related to the training intervention. In addition, chromosomal damage, such as micronuclei frequencies or NPBs showed a trend to decrease in all three groups28. The supplementation group acquired improvements in plasma vitamin B12 and folate status in erythrocytes28.…”

“…In addition, chromosomal damage, such as micronuclei frequencies or NPBs showed a trend to decrease in all three groups28. The supplementation group acquired improvements in plasma vitamin B12 and folate status in erythrocytes28. While acute exercise increases the concentration of cfDNA within hours post-exercise, it is being quickly eliminated and returns to normal values within a few days16.…”

“…Published data on this study have shown an improvement in physical performance in individuals undergoing an exercise training intervention, compared to sedentary controls27, as well as a trend for a decreased chromosomal and DNA damage in the entire study population28. The main aim of this paper was to investigate a potential relationship between blood telomere length, cfDNA and unconjugated bilirubin at baseline and after a 6-month training intervention.…”

Elastic Band Exercises Improved Activities of Daily Living and Functional Fitness of Wheelchair-bound Older Adults with Cognitive Impairment

“…21 Another study in Australia found for 97 older adults that 6-month elastic band upper and lower limbs exercise training (2 times a week, 45 minutes each time) improved sit-to-stand ability and walking distance in 6 minutes. 22 In addition, Chen et al 23 found that elastic band exercises improved the daily living activities and functional fitness of 114 institutional older adults in wheelchairs. 23 Unfortunately, for older adults who had to rely on wheelchairs, regular exercises were seldom offered in the institutions.…”