The Effect of Small Amounts of Alcohol on the Clinical Course of Chronic Pancreatitis

Lankisch, Mark; Imoto, Mami; Layer, Peter; DiMagno, Eugene P.

doi:10.4065/76.3.242

Cited by 65 publications

(30 citation statements)

References 15 publications

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“…Recent investigations have shown that even small amounts of alcohol damage the pancreas [9]. Our classification has no influence on the incidence rate of chronic pancreatitis, but perhaps on the separation into alcohol-induced chronic pancreatitis and idiopathic chronic pancreatitis, and perhaps some of the cases of acute pancreatitis classified as unknown etiology or idiopathic acute pancreatitis may have belonged into the alcohol group.…”

Section: Discussionmentioning

confidence: 99%

Epidemiology of pancreatic diseases in Lüneburg county

et al. 2002

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Section: Discussionmentioning

confidence: 99%

Epidemiology of pancreatic diseases in Lüneburg county

et al. 2002

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“…This is probably related to the fact that alcoholic pancreatitis is directly related to the amount of alcohol consumed 28 . Lankish et al 29 found that continuous alcohol intake accelerates the disease and is associated with diabetes and greater pain, steatorrhea, morbidity, and mortality.…”

Section: Discussionmentioning

confidence: 99%

Alcoholic chronic pancreatitis: A quality of life study

et al. 2016

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A B S T R A C T ObjectiveTo compare the quality of life between patients with alcoholic chronic pancreatitis and controls, and between diabetic and non-diabetic patients, correlating clinical, sociodemographic, and nutritional factors with their quality of life scores. MethodsForty-three outpatients of the pancreas and biliary tract clinic diagnosed with alcoholic chronic pancreatitis were assessed. Quality of life was measured by the Brazilian version of the Short Form-36. The control group consisted of 43 healthy companions. Nutritional status was classified according to body mass index and triceps, biceps, suprailiac, and subscapular skinfold thicknesses, using the appropriate methods. The percentage of body fat was given by adding the four skinfold thicknesses and by bioelectrical impedance analysis. The statistical tests included the Chi-square, Mann-Whitney, and Spearman's correlation tests, with the significance level set at p<0.05. ResultsThe sociodemographic variables of the case and control groups did not differ. Quality of life was lower in alcoholic chronic pancreatitis patients than in controls. The only quality of life domain that differed between diabetics and non-diabetics was functional capacity, lower in diabetics (p=0.022). Smoking duration, alcohol intake in grams, and time since pancreatic surgery correlated negatively with the quality of life of alcoholic chronic pancreatitis patients. Old age, skinfold thicknesses, and percentage of body fat correlated positively with quality of life.

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“…In a study of non-alcoholic chronic pancreatitis, Lankisch et al [40] showed that alcohol consumption of ! 50 g/day tended to accelerate the disease process, and in some cases increased the severity, just as higher alcohol consumption did.…”

Section: Pancreasmentioning

confidence: 99%

Moderate Alcohol Consumption and the Gastrointestinal Tract

Taylor

Rehm²,

Gmel³

2005

Dig Dis

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Background: A high alcohol intake is significantly associated with diseases of the gastrointestinal tract, but less is known about the effects of moderate consumption, specifically moderate average volume of alcohol consumption. Methods: A systematic computer-assisted literature review was completed in order to review current scientific knowledge surrounding this topic. Results: Moderate alcohol consumption is associated with a number of gastrointestinal health risks, including liver diseases, oropharyngeal cancer, esophageal cancer and pancreatitis but may play a positive role in gastritis and cholelithiasis. Conclusion: Moderate alcohol consumption may play a positive or negative role in disease etiology, but the overall conclusion is that moderate alcohol intake is not a high risk factor for many of the gastrointestinal diseases associated with high levels of consumption. The etiology of alcohol diseases is also linked to patterns of drinking, so this is an important area for future research in this area.

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The Effect of Small Amounts of Alcohol on the Clinical Course of Chronic Pancreatitis

Cited by 65 publications

References 15 publications

Epidemiology of pancreatic diseases in Lüneburg county

Epidemiology of pancreatic diseases in Lüneburg county

Alcoholic chronic pancreatitis: A quality of life study

Moderate Alcohol Consumption and the Gastrointestinal Tract

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