2017
DOI: 10.2174/1874120701711010085
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The Effect of Strain Hardening on the Dynamic Response of Human Artery Segments

Abstract: Background:When subjected to time-dependent blood pressure, human arteries undergo large deformations, exhibiting mainly nonlinear hyperelastic type of response. The mechanical response of arteries depends on the health of tissues that comprise the artery walls. Typically, healthy arteries exhibit convex strain hardening under tensile loads, atherosclerotic parts exhibit stiffer response, and aneurysmatic parts exhibit softening response. In reality, arterial dynamics is the dynamics of a propagating pulse, or… Show more

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Cited by 8 publications
(6 citation statements)
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“…The arterial wall in our model is, therefore, divided into different regions (Fig 1b and 1c) with different constitutive laws. Similar to Charalambous et al [31], we employ the strain-hardening Skalak (SK) model [26] for the healthy arterial wall:…”
Section: Physical Ingredientsmentioning
confidence: 99%
See 1 more Smart Citation
“…The arterial wall in our model is, therefore, divided into different regions (Fig 1b and 1c) with different constitutive laws. Similar to Charalambous et al [31], we employ the strain-hardening Skalak (SK) model [26] for the healthy arterial wall:…”
Section: Physical Ingredientsmentioning
confidence: 99%
“…The SK and NH laws are described as areal energy densities ω SK and ω NH , respectively. Both models have a surface elastic shear modulus κ s , and the SK model has an area dilation modulus κ α (for the sake of simplicity, we choose κ s = κ α [31]). I 1 and I 2 are strain invariants depending on the local principal in-plane stretch ratios λ 1 and λ 2 as…”
Section: Physical Ingredientsmentioning
confidence: 99%
“…Arteries under prolonged stresses and strains become stiffer and less elastic. [2526] As such, restoration of normal cervical lordosis may result in a slower response from arteries that were stressed and strained the most and a faster response from arteries that were stressed and strained the least.…”
Section: Discussionmentioning
confidence: 99%
“…The arterial wall in our model is, therefore, divided into different regions (Fig 1b and 1c) with different constitutive laws. Similar to Charalambous et al [31], we employ the strain-hardening Skalak (SK) model [23] for the healthy arterial wall:…”
Section: Physical Ingredientsmentioning
confidence: 99%
“…Additionally, we employ a finite bending resistance κ b to account for the finite wall thickness. The two free parameters κ s and κ b are related to the Young's modulus E, wall thickness d and Poisson ratio ν according to [31,32]…”
Section: Physical Ingredientsmentioning
confidence: 99%