The effect of subacromial injections of autologous conditioned plasma versus cortisone for the treatment of symptomatic partial rotator cuff tears

Wehren, Lutz von; Blanke, Fabian; Todorov, Atanas; Heisterbach, Patricia; Sailer, Jannis; Majewski, Martin

doi:10.1007/s00167-015-3651-3

Cited by 74 publications

(82 citation statements)

References 49 publications

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“…после начала лечения оцениваемые показатели в обеих группах пациентов не имели статистически значимых различий. Последнее относилось и к оценке МРТ-признаков тендинопатии по классификации M. Scarpone с соавторами, которые имели очевидную положительную динамику в обеих группах пациентов [19].…”

Section: Discussionunclassified

“…Результаты лечения пациентов с тендинопатиями различной локализации определяются многими факторами, среди которых анатомические и биомеханические характеристики сухожилий имеют не менее важное значение, чем методики получения и протоколы использования PRP. указанные обстоятельства объясняют не только бóльшую эффективность PRP-терапии, например, при тендинопатии ахиллова сухожилия, связки надколенника, разгибателей кисти в области прикрепления к наружному надмыщелку плечевой кости, но и сохраняющиеся сомнения в положительных результатах применения плазмы в случаях тендинопатии сухожилий вращательной манжеты плеча [6,14,17,18,19].…”

Section: методика оценки результатовunclassified

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PRP-Therapy for Tendinopathies of Rotator Cuff and Long Head of Biceps

Маланин

Норкин

Трегубов

et al. 2019

Traumatology and Orthopedics of Russia

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Relevance. Owing to its controlling action on the inflammatory process, pain-relieving and reparative effects the RPR-therapy became quite demanded for treatment of certain types of tendinopathies specified by prevalence of degenerative process and poor reparative potential. Purpose of the study — to evaluate the efficiency of PRP-therapy in patients with tendinopathies of rotator cuff (RC) long head of biceps (LHB) tendons. Material and Methods. The paper presents the results of two-center prospective study for application of autologous platelet rich plasma in treatment of 122 patients: 53 men and 69 women aging 46.8±6.8 years who suffered RC tendinopathy (66%), subacromial impingement syndrome and RC tendinopathy (17%) and LHB tendinopathy (17%). Treatment outcomes were evaluated in 1, 3 and 6 months after PRP-therapy using various scales — VAS, UCLA , DASH, — and instrumental examination methods (US, MRI). Results. The authors observed statistically significant improvement in pain and functional scores in all three groups as compared to reported scores prior to PRP-therapy during 6 months follow up. During this period of evaluation, the scores of UCLA and DASH in patients with RC tendinopathy improved at 8.6 and 36.4 points, with subacromial impingement syndrome and RC tendinopathy — at 9.6 and 38.8 points, with LHB tendinopathy — at 11.5 and 44.1 point, respectively. The most notable reduction of pain syndrome by VAS was achieved in treatment of LHB tendinopathy (at 5.4 points) and RC tendinopathy (at 5.2 point). The highest average scores of satisfaction with treatment outcomes were reported in patients with RC tendinopathy (2.3) and LHB tendinopathy (2.2). MRI and ultrasound examinations after PRP-therapy demonstrated improved structure of RC and LHB tendons — decreased or eliminated swelling, areas of hypoechoic signal. Conclusion. PRP-therapy in patients with RC and LHB tendons and with subacromial impingement syndrome with RC tendinopathy significantly reduces severity of pain and improved the shoulder joint function with positive dynamics during 6 months follow up.

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Section: Discussionunclassified

Section: методика оценки результатовunclassified

PRP-Therapy for Tendinopathies of Rotator Cuff and Long Head of Biceps

Маланин

Норкин

Трегубов

et al. 2019

Traumatology and Orthopedics of Russia

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“…Bizim çalışmamızla oldukça benzerlik gösteren bir çalışmada ise rotator kaf tendon patolojisi olan bir gruba PRP bir gruba ise kortizon uygulanmıştır. Erken dönemde PRP grubunda ağrı ve fonksiyonel indekslerde daha fazla düzelme olduğu ancak altıncı ayda aralarında fark olmadığı kaydedilmiştir (24). Bizim çalışmamızda da benzer şekilde VAS skorlarında ikinci ay kontrolünde PRP grubunda daha fazla azalma olduğu ve bu farkın istatistiksel olarak anlamlı olduğu saptanmıştır.…”

Section: Discussionunclassified

Comparison of Platelet-rich Plasma and Cortisone Injections Administered Under Ultrasonography Guidance in Rotator Cuff Tendon Pathologies

Subaşı¹

2019

Tod

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Objective: Rotator cuff tendon pathologies are the most frequently diagnosed disease group among the causes of shoulder pain. The aim of this study was to compare the results of platelet-rich plasma (PRP) and cortisone treatments applied to patients who admitted to our outpatient clinic with the diagnosis of Rotator cuff syndrome. Materials and Methods: A total of 40 patients with no shoulder movement restriction and shoulder pain longer than 3 months were included in the study. Pain symptoms of the patients were evaluated with Visual Analogue Scale (VAS) and functional status with the disabilities of the arm, shoulder and hand score (Quick-DASH). Results: Statistically significant improvements were observed in the VAS and Quick-DASH scores at the first and second month controls (according to the first month and pre-treatment) in the evaluations of the both groups (p<0.01). In the statistical study comparing clinical recovery in both groups, it was found that there was a further decrease in the PRP group at the second month control only in the VAS scores (p=0.007) and this difference was found to be statistically significant, while the decrease in the Quick-DASH scores was found to be statistically similar (p=0.007). Conclusion: In this study, we concluded that PRP and cortisone injections were effective in rotator cuff lesions. We believe that the PRP therapy is a good alternative to rotator cuff lesions in patients with comorbid diseases or in patients who cannot be treated with cortisone because of the adverse effects.Amaç: Rotator kaf tendon patolojileri omuz ağrısı yapan nedenler arasında en sık saptanan hastalık grubunu oluşturmaktadır. Rotator kaf sendromu tanısı ile polikliniğimize başvuran hastalara uygulanan plateletten zengin plazma (PRP) ve kortizon tedavilerinin sonuçlarının karşılaştırılması amaçlanmıştır. Gereç ve Yöntem: Çalışmaya ileri derecede omuz hareket kısıtlılığı olmayan, 3 aydan uzun süreli omuz ağrısı olan toplam 40 hasta dahil edildi. Hastaların ağrı yakınması Visüel Analog Skala (VAS) ve fonksiyonel durumu ise kol, omuz ve el sorunları anketi (Quick-DASH) ile değerlendirildi. Bulgular: Her iki grubun kendi içindeki değerlendirmelerinde birinci ay ve ikinci ay kontrollerinde (birinci aya ve tedavi öncesine göre) VAS ve Quick-DASH skorlarında istatistiksel olarak anlamlı düzelmeler kaydedildi (p<0,01). Her iki grupta oluşan klinik iyileşmenin kıyaslandığı istatistiksel çalışmada ise sadece VAS skorlarında 2. ay kontrolünde PRP grubunda daha fazla azalma olduğu ve bu farkın istatistiksel olarak anlamlı olduğu saptandı (p=0,007). Quick-DASH skorlarındaki azalmanın ise istatistiksel olarak benzer olduğu saptandı (p=0.007). Sonuç: Sonuç olarak yaptığımız çalışmada rotator kaf lezyonlarında PRP ve kortizon enjeksiyonları tedavilerinin etkili olduğu sonucuna vardık. Komorbid hastalıkları olan kişilerde, yan etkileri nedeniyle kortizon tedavisi uygulanamayan hastalarda PRP tedavisinin rotator kaf lezyonlarında iyi bir tedavi alternatifi olduğu kanısındayız. Anahtar kelimeler: Rotator kaf lezyonl...

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“…Interventional radiology offers minimally invasive image guided therapy for a growing range of nonvascular diseases. Percutaneous image guided peritendinous injections of various drugs including platelet rich plasma (PRP) that contains various growth factors & cytokines that stimulate healing of bone and soft tissues are now frequently used in sports related injuries (23,24). I believe that the future of musculoskeletal procedures is bright with promise.…”

Section: Discussionmentioning

confidence: 99%

Role of percutaneous nonvascular Interventional Radiology treatments in musculoskeletal lesions

Srivastava

2016

Annals of the National Academy of Medical Sciences (India)

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SUMMARYMany new, minimally invasive interventional radiology procedures are now viable alternatives to traditional invasive therapy. These interventional radiological procedures can be performed in the outpatient setting and the overall cost to the patient may be less in the long run. Radiofrequency and Laser ablation techniques are now widely used and rapidly expanding technologies in the interventional radiology used in the treatment of tumours, varicose vein and lumbar disc treatment. Similarly percutaneous vertebroplasty (PVP) is used in the treatment of spinal lesions and osteoporotic vertebral collapse. The knowledge of these procedures is vital as medicine moves into minimally invasive procedures with targeted treatments as these procedures offer less risk, less pain and less recovery time compared to various surgical procedures.In this presentation I would like to present my work related to percutaneous vertebroplasty (PVP) in spinal lesions, percutaneous Laser disc decompression (PLDD) in the treatment of chronic discogenic low back pain and percutaneous radiofrequency ablation (RFA) in musculoskeletal lesions. The technique, results and long term outcomes of these newer procedures will be discussed.

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The effect of subacromial injections of autologous conditioned plasma versus cortisone for the treatment of symptomatic partial rotator cuff tears

Abstract: Therapeutic study, Level III.

Cited by 74 publications

References 49 publications

PRP-Therapy for Tendinopathies of Rotator Cuff and Long Head of Biceps

PRP-Therapy for Tendinopathies of Rotator Cuff and Long Head of Biceps

Comparison of Platelet-rich Plasma and Cortisone Injections Administered Under Ultrasonography Guidance in Rotator Cuff Tendon Pathologies

Role of percutaneous nonvascular Interventional Radiology treatments in musculoskeletal lesions

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