“…(Huguet & Dellacherie, 1996;Jia et al, 2017;Lulevich & Vinogradova, 2004;Polk, Amsden, De Yao, Peng, & Goosen, 1994a) Temperatures Release, activity and morphology (Cui, Zhang, Lin, Li, & Jin, 2008;Dianawati, Lim, Ooi, & Shah, 2017;Kuck, Wesolowsk, & Norena, 2017;Kohler, Biesheuvel, Weinkamer, Mohwald, & Sukhorukov, 2006;Kohler, Shchukin, Mohwald, & Sukhorukov, 2005;Liu et al, 2008;Ye, Wang, Liu, & Tong, 2005) Particle sizes Loading, aggregation, drug release and retention (Berkland, King, Cox, Kim, & Pack, 2002;Foda & El, 1989;Lemos et al, 2017;Morris & Warburton, 1984;Sen, Bahadur, Mazumder, & Bhattacharya, 2012) Additives and others Strength, release, yield, encapsulation efficiency, membrane porosity, etc. (Angelova & Hunkeler, 2001;Bartkowiak, 2002;Fang, Li, & Liu, 2010;Jono et al, 1997;Luzzi & Gerraughty, 1967;Simón, Rodriguez, & Sanchez, 2013;Varma, Kaushal, Garg, & Garg, 2004;Wang, Hu, Liu, He, & Guo, 2011;Wong et al, 2015;Yamaguchi et al, 2002) F I G U R E 4 Schematic diagram of chitosan and sodium alginate polyelectrolyte membrane formation (Liu et al, 2008) (Cui et al, 2008). Therefore, the temperature not only affects the structures and properties of the microcapsule shells, but also affects the sustained release characteristics of the loaded contents.…”