Children with specific learning disabilities exhibit lower cognitive flexibility compared to typically developing children. The purpose of the present study was to investigate the effect of Transcranial Direct Current Stimulation (TDCS) on Cognitive Flexibility of children with learning disabilities in Tehran. A semi-experimental design with pre-test, post-test, and control group study was conducted. The study population consisted of all students with Specific Learning Disorders in Tehran during the academic year 2022-2023. A total of 30 students, aged from 7 to 12, were selected as the sample group using the purposeful sampling method. We randomly divided the participants into two control and experimental groups (n = 15 each). The research tool was the Wisconsin Card Sorting Test. The experimental group underwent a stimulation protocol involving a weak direct current. The protocol consisted of 10 sessions, with the initial five sessions utilizing a low intensity of 1mA, followed by a slight increase to 1.5mA for the remaining five sessions. The anode electrode, measuring 5 x 5 cm, was inserted in the left dorsolateral prefrontal cortex (DLPFC) at the F3 location, while the cathode electrode, also measuring 5 x 5 cm, was placed on the right ventromedial prefrontal cortex (VMPFC) at the Fp2 location. Each session lasted for 20 minutes. Data were analyzed using one-way analysis of multivariate covariance analysis (MANCOVA) and independent t-tests. The results showed that TDCS has been effective in Cognitive Flexibility.