During the cyclic deformation of ½ " 579, Al single crystals with a high stacking fault energy produced slip bands that were characterized by wavy slip. Its cyclic stress response curve demonstrated that the specimen experienced hardening-softening-secondary hardening in sequence with repeated fluctuation stresses usually less than 10 MPa, which is far lower than those of Cu, Ni, and Ag single crystals. Finally, the whole surface of the Al single crystals was covered with intense intrusion and extrusion, and the cell structure is the most typical dislocation arrangement. These cells mainly comprise loose clusters of dislocations, which move more freely. In the center of the cell, the dislocation density is relatively low, and most dislocations concentrate in the cell wall. At room temperature, compared with cyclically deformed Cu, Ni, and Ag single crystals, the cyclic deformation behaviors of Al single crystals show significant differences, which are highlighted in this study.