The effect of temperature change on fluoride uptake from a mouthrinse by enamel specimens

Abstract

Objective: The aim of this study was to examine the effect of temperature on fluoride uptake by enamel specimens from a 0.05% NaF-fluoridated mouthrinse (Oral-B Advantage; Oral-B Laboratories, Newbridge, UK).Methods: Enamel specimens were prepared from extracted human maxillary central incisors. A fluoride-specific ion electrode was used to measure the uptake from a 2 ppm fluoride solution containing 50.0 mL of distilled water, total ion strength adjustment buffer, and fluoridated rinse at 3 different temperatures (room temperature, 25°C; human body temperature, 37°C; hyper-fever temperature, 43°C). One-way analysis of variance and least significant difference were used to assess intragroup and intergroup differences (P<.05).Results: The study found that both the amount and the rate of fluoride uptake increased significantly with increase in temperature. This effect was particularly noticeable at 43°C.Conclusions: The temperature of the NaF mouthrinse may easily and safely be increased beyond room temperature by placing a container of the NaF mouthrinse in a bowl of hot water, allowing greater fluoride penetration into the enamel from the mouthrinse when used at home as a routine prophylactic agent. (Eur J Dent 2012;6:361-369)

Artificial Caries Resistance in Enamel after Topical Fluoride Treatment and 445 nm Laser Irradiation

“…Few studies reported the temperature-dependent fluoride uptake by the enamel. Baglar et al [25] found in their study that fluoride uptake by enamel from NaF mouth rinse increased by preheating the mouth rinse from 25°C to 37°C and 43°C, and the fluoride concentration in the mouth rinse was decreased after 1 min to be 2, 1.79, and 1.25 ppm, respectively. Barrancos [26] also reported this finding when the room temperature was increased.…”

Comparative Fluoride Release and Antimicrobial Analysis of Commercial and Experimental Bioactive Glass/Nano-Oxide-Based Dentifrices

“…1 Availability and stability of fluoride in dentifrices are basic requirements for effectiveness against tooth decay. 2,3 Fluoride ions can inhibit Eur J Dent 2020;14:38-44 the production of bacterial acids in dental plaque due to the influx of hydrogen fluoride into bacterial cells, and the dissociation to the H + and Fions in the cytoplasm. 4 For caries control, dentifrice formulation should contain a minimum of 1000 parts per million (ppm) fluoride, which must be in a soluble form to impart the anticaries effect.…”

“…7 Dentifrice composition plays a crucial role in disabling free fluoride ions, which may lead to creation of a low-solubility product with a diminished anticaries outcome. 2,3 Currently, there are no regulations to specify how much of total fluoride should be maintained in a dentifrice formulation. 5 There has been a growing interest in the use of "smart" bioactive materials (i.e., amorphous calcium phosphate, hydroxyapatite, bioactive glass, etc.)…”