The effect of the COVID-19 pandemic lockdown on symptom severity in school children with house dust mite-sensitized allergic rhinitis

Çelik, Figen Çelebi; Soyöz, Özgen; Sancakli, Ozlem; Bölük, Selime Özen; Taşkırdı, Ilke; Kaya, Mehmet; Haci, Idil Akay; Demir, Ayça; Karkıner, Canan Şule Ünsal; Can, Demet

doi:10.1016/j.reval.2022.07.006

Cited by 3 publications

(4 citation statements)

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“…In a volunteer group of non-allergic rhinitis patients, increased nasal symptoms and down-regulation of type I and III interferon levels in the nasal mucosa were found with increased exposure to airborne pollen. Again, in a large cohort of patients, the number of rhinovirus positive cases was associated with airborne birch pollen concentrations (40). All these results support the increase in epithelial barrier dysfunction due to the increase in the amount of pollen.…”

Section: Discussionsupporting

confidence: 62%

“…During periods of elevated pollen concentrations, both patients with pollen allergies and non-allergic individuals often seek medical assistance due to severe respiratory tract infections. Studies examining the influence of pollen on antiviral immunity have revealed that the expression of antiviral genes weakens, and pulmonary viral titers increase when mice infected with RSV are simultaneously exposed to pollen (39,40). In a volunteer group of non-allergic rhinitis patients, increased nasal symptoms and down-regulation of type I and III interferon levels in the nasal mucosa were found with increased exposure to airborne pollen.…”

Section: Discussionmentioning

confidence: 99%

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The relationship between aeroallergen sensitivity variations and Covid 19 in patients with rhinitis

Basa Akdoğan,

Gültuna

2023

Med Sci Discov

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Objective: There have been studies evaluating the association between AR and COVID-19 infection, but these studies did not evaluate the sensitisation of patients. The objective of this study was to examine the impact of allergen sensitisation on the transmission of viral infections and the progression of the disease. Material and Methods: Rhinitis patients admitted to the Adult Allergy Outpatient Clinic between April and June 2021 were included in the study. Aeroallergen sensitisation and COVID-19 disease status of the patients were evaluated. Results: Data were collected from 260 patients. It was determined that 23.8% (n=62) of the patients had COVID-19 and 17.7% (n=11) had COVID-19 pneumonia. This rate was higher than the incidence of COVID-19 in the general population. The rate of COVID-19 infection was significantly higher in patients with pollen allergy compared to other groups (p=0.049). When the COVID-19 transmission periods of the patients were analysed, it was observed that 55% of them were infected between March and September in accordance with the pollen map. Patients taking steroids (INCS or ICS) did not have an increased risk of COVID infection, and concomitant asthma did not pose an increased risk. Having chronic diseases was found to be a risk factor. Conclusions: This study provides clinical evidence of an increased frequency of infection in AR patients, especially in AR patients with pollen allergy. This result is valuable as it is a data not presented in existing studies. We also think that the risk of COVID-19 increases with pollen exposure. As pollen can suppress antiviral immunity, we recommend that chronic disease groups pay special attention to prevention methods, especially when pollen and respiratory virus seasons overlap.

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Section: Discussionsupporting

confidence: 62%

Section: Discussionmentioning

confidence: 99%

The relationship between aeroallergen sensitivity variations and Covid 19 in patients with rhinitis

Basa Akdoğan,

Gültuna

2023

Med Sci Discov

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“…Studies have shown that those sensitized to outdoor allergens benefit from face mask usage. [17][18][19]22,24,25,27 In contrast, those sensitized to indoor allergens showed indifference when wearing a face mask and worsening symptoms during lockdown. 2,18,19,25 More than 45% of respondents agreed/ strongly agreed that the type of face mask available in the market has a role in giving them the desired reduction of symptoms.…”

Section: Attitude Domainmentioning

confidence: 99%

“…Previous studies have shown that during the COVID-19 global pandemic, there has been a decrease in allergic rhinitis symptoms among patients 2,6,[17][18][19][20][21][22][23][24][25][26][27][28][29] This can be attributed to two possible reasons: first, the reduced exposure to allergens because of the COVID-19 lockdown and avoidance of crowded places. Second, the use of face masks as per COVID-19 safety guidelines.…”

Section: Symptoms Of Allergic Rhinitis Domainmentioning

confidence: 99%

A cross-sectional survey on the experience of people with allergic rhinitis amidst COVID-19 pandemic: The impact of the facemask: A pilot study

Mazrouei,

Elnour,

Hajal

et al. 2023

PHARMPRACT

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Background: Since outbreak of COVID-19 pandemic, almost whole world asked to wear the facemask especially in the public areas as a precaution to avoid the transmission of the disease, and curbs the pandemic. Looking from another perspective, we need to consider the effect of the facemask in reducing allergic rhinitis symptoms. Objective: The current study objective was to assess the impact of facemasks on the symptoms of allergic rhinitis in subjects who were obligatory using facemask due to the COVID-19 pandemic. Methods: The current study was ethically approved self-administered validated survey (Cronbach Alfa 0.81) comprised of 28-items to assess the impact of wearing the facemask, and whether there was an improvement in symptoms of allergic rhinitis. The outcome measure was the responses to the four domains (knowledge, attitude, symptoms, and help/advice) measured on Likert scale to assess the responses of subjects with allergic rhinitis during the COVID -19 pandemic. Results: 82 respondents (mean age was 22.59 ±2.77 years) have completed the survey, of which 73 females (89%) and (52/82, 63.4%) university students. 29 (35.4%), stated that the fabric facemask is useful in reduction of symptoms. 44 (53.7%) believe that the surgical mask N95 is very beneficial in the reduction of symptoms. There was a significant difference in knowledge levels for both eye and nasal symptoms' reduction responses (P <0.001). Tukey's HSD (honestly significant difference) used to determine the specifics of the variances (differences in multiple means) in symptom reduction. For eye symptoms, the analysis revealed that respondents who reported that they had reduced symptoms had higher knowledge scores (6.74±2.7) than those who reported no reduction in allergic symptoms (mean ±SD: 4.96±3.2). The lowest score was associated with respondents that were uncertain regarding their symptom alleviation (mean ±SD: 4.53±3.1). For nasal symptoms, the analysis revealed that respondents who reported that they had reduced symptoms had higher knowledge scores (7.03±2.7) than those who reported no reduction in allergic symptoms (3.94±2.5). Conclusion: Our results reveal that facemask usage may reduce allergic rhinitis symptom severity in chronically affected individuals with intermittent disease. The study supports the hypothesis that facemask may reduce atopic allergic responses.

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Different Aspects of COVID‐19: “Stay at Home” Increased Cat and Mite Sensitivity in Preschool Children

Karavaizoglu,

Suleyman,

Dolu

et al. 2024

Pediatric Pulmonology

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BackgroundIndoor allergen exposure and senitization is expected to increase significantly during the COVID‐19 pandemic. The aim of this study was to assess the impact of this altered allergen exposure on allergen sensitivity patterns in children with asthma.MethodsDemographic data, clinical characteristics, and laboratory findings of asthmatic children aged 5 years and younger were assessed May 2019 to May 2020, 1 year after the start of lockdown measures. Those asthmatic children were compared with age‐ and sex‐matched asthmatic peers assessed before the pandemic. Group I included asthmatic children who underwent skin testing within 12 months of the start of the lockdown (n = 112), while Group II included asthmatic children whose skin testing was done before the lockdown (n = 224).ResultsA total of 336 preschool children diagnosed with asthma were evaluated. House dust mite (HDM) and animal dander (cat, dog) senitization rates were significantly higher in Group I than in Group II (66.1% vs. 42.9%; OR: 2.5, 95% CI: 1.6–4.1, p < 0.001 and 8.0% vs. 1.3%; OR: 6.4, CI: 1.7–24.2, p = 0.006, respectively). However, the number of asthma attacks requiring systemic corticosteroid treatment was higher in Group I than in Group II (p = 0.001). The duration of lockdown emerged as a significant risk factor for HDM senitization (p < 0.001, OR: 2.6, 95% CI: 1.6–4.1) and animal allergen senitization (p = 0.006, OR: 6.4, 95% CI: 1.7–27.3).ConclusionDuring the pandemic, senitization to indoor allergens, including HDM and animal dander, increased significantly in asthmatic children. This may be attributed to changes in lifestyle, increased time spent indoors and increased pet ownership.

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The effect of the COVID-19 pandemic lockdown on symptom severity in school children with house dust mite-sensitized allergic rhinitis

Cited by 3 publications

References 24 publications

The relationship between aeroallergen sensitivity variations and Covid 19 in patients with rhinitis

The relationship between aeroallergen sensitivity variations and Covid 19 in patients with rhinitis

A cross-sectional survey on the experience of people with allergic rhinitis amidst COVID-19 pandemic: The impact of the facemask: A pilot study

Different Aspects of COVID‐19: “Stay at Home” Increased Cat and Mite Sensitivity in Preschool Children

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