The effect of TopClosure® TRS in the treatment of large abdominal wall defect

Wang, Xiaoli; Zhu, Zhanyong; Zhao, Yang; Yu, Ming; Topaz, Moris

doi:10.1007/s00238-019-01516-y

Cited by 2 publications

(2 citation statements)

References 17 publications

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“…Abdominal wall defects are often caused by infection or dehiscence of post-operative incisions without involving the full-thickness abdominal wall. Five retrospective studies reported the application of TopClosure® [ 82 ], KeKe® [ 75 ], Proxiderm® [ 30 ] and homemade devices, such as rubber bands [ 38 ] and nice knots [ 2 ], in 24 patients. Four retrospective studies met the inclusion criteria for the meta-analysis of the mean healing time of abdominal wall defects [ 30 , 38 , 75 , 82 ].…”

Section: Resultsmentioning

confidence: 99%

“…Five retrospective studies reported the application of TopClosure® [ 82 ], KeKe® [ 75 ], Proxiderm® [ 30 ] and homemade devices, such as rubber bands [ 38 ] and nice knots [ 2 ], in 24 patients. Four retrospective studies met the inclusion criteria for the meta-analysis of the mean healing time of abdominal wall defects [ 30 , 38 , 75 , 82 ]. The pooled median wound closure time was 12.853 days (95% CI = 9.444-16.227, I 2 = 72%, p = 0.01) ( Figure 7a ).…”

Section: Resultsmentioning

confidence: 99%

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Efficacy and safety of external tissue expansion technique in the treatment of soft tissue defects: a systematic review and meta-analysis of outcomes and complication rates

Tong

Zhang

et al. 2022

Burns &Amp; Trauma

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Background Currently, various external tissue expansion devices are becoming widely used. Considering the scarcity of relevant application standards, this systematic review was performed to explore the effectiveness and safety of external tissue expansion techniques for the reconstruction of soft tissue defects. Method A systematic review and meta-analysis on the efficacy and safety of external tissue expansion technique was conducted. A comprehensive search was performed in the following electronic databases: PubMed/Medline, Embase, Cochrane Library (Wiley Online Library), and Web of Science. Studies reporting patients with soft tissue defects under the treatment of external tissue expansion technique were included. Results A total of 66 studies with 22 different types of external tissue expansion devices met the inclusion criteria. We performed a descriptive analysis of different kinds of devices. A single-arm meta-analysis was performed to evaluate the efficacy and safety of the external tissue expansion technique for different aetiologies. The pooled mean wound healing time among patients with defects after fasciotomy was 10.548 days [95% confidence interval (CI) = 5.796–15.299]. The pooled median wound healing times of patients with defects after excisional surgery, trauma, chronic ulcers and abdominal defects were 11.218 days (95% CI = 6.183-16.253), 11.561 days (95% CI = 7.062-16.060), 15.956 days (95% CI = 11.916-19.996) and 12.853 days (95% CI=9.444-16.227), respectively. The pooled wound healing rates of patients with defects after fasciotomy, excisional surgery, trauma, chronic ulcers and abdominal defects were 93.8% (95% CI=87.1-98.2%), 97.2% (95%CI=92.2-99.7%), 97.0% (95%CI=91.2-99.8%), 99.5% (95%CI=97.6-100%), and 96.8% (95%CI=79.2-100%), respectively. We performed a subgroup analysis in patients with diabetic ulcers and open abdominal wounds. The pooled median wound healing time of patients with diabetic ulcers was 11.730 days (95% CI = 10.334-13.125). The pooled median wound healing time of patients with open abdomen defects was 48.810 days (95% CI = 35.557–62.063) and the pooled successful healing rate was 68.8% (95% CI = 45.9-88.1%). A total of 1686 patients were included, 265 (15.7%) of whom experienced complications. The most common complication was dehiscence (n = 53, 3.14%). Conclusions Our systematic review is the first to demonstrate the efficacy and safety of external tissue expansion in the management of soft tissue defects. However, we must interpret the meta-analysis results with caution considering the limitations of this review. Large-scale randomized controlled trials and long-term follow-up studies are still needed to confirm the effectiveness and evaluate the quality of healing.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Efficacy and safety of external tissue expansion technique in the treatment of soft tissue defects: a systematic review and meta-analysis of outcomes and complication rates

Tong

Zhang

et al. 2022

Burns &Amp; Trauma

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Treatment of limb skin defect with self-made skin distractor

Lei,

Kai,

Yanlong

et al. 2024

Preprint

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Objective To investigate the effect of self-made skin distractor in the treatment of limb skin defects. Methods From September 2018 to January 2020, 15 cases of limb skin defects (16 wounds) were treated with self-designed skin distractor, including 13 males and 2 females, with an average age of 42 years (range, 9-73 years). The smallest area of skin defect was 6cm×3cm, the largest was 32cm ×7cm, with an average of 72.4cm2. The wound healing was observed, complications and the time of use of the distractor were recorded. Results All patients were followed up for 6-12 months with an average of 9.2 months. Of the 16 wounds in 15 patients, 2 wounds were closed in one stage during operation, 13 wounds were delayed in primary closure. Skin incision occurred in 1 case, but the wound closure was not affected；One wounds were not closed completely, because the skin was cut by Kirschner wire, and could not be stretched continously. The remaining wounds were closed by skin grafting. Another case also had skin cutting was occurred in another case, but the wound closure was not affected. No skin stretch was terminated due to pain. All wounds were healed. The elasticity and color of the skin on the wound surface were not different from the surrounding skin. The movement of the adjacent joints was basically normal. Conclusion The self-made skin stretcher is simple in structure and easy to use. It provides a reliable and effective method for the treatment of skin defects of limbs.

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The effect of TopClosure® TRS in the treatment of large abdominal wall defect

Cited by 2 publications

References 17 publications

Efficacy and safety of external tissue expansion technique in the treatment of soft tissue defects: a systematic review and meta-analysis of outcomes and complication rates

Efficacy and safety of external tissue expansion technique in the treatment of soft tissue defects: a systematic review and meta-analysis of outcomes and complication rates

Treatment of limb skin defect with self-made skin distractor

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