The effect of triamcinolone with tetracycline on the dental pulp and apical periodontium

Ehrmann, E. H.

doi:10.1016/0022-3913(65)90074-0

Cited by 43 publications

(35 citation statements)

References 17 publications

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“…67 Ehrmann et al 80 have shown that Ledermix paste provides greater postoperative pain relief compared to teeth medicated with calcium hydroxide, and this has been confirmed by several other studies. 65,78,79,81,82 As an example, Negm 78 reported that more than 85 per cent of cases had complete relief of pain after a one hour interval and more than 93 per cent were free of pain within 24 hours of treatment.…”

Section: (B) Antibioticsmentioning

confidence: 99%

“…Ledermix paste was developed by Schroeder and Triadan in 1960, and was released for sale in Europe by Lederle Pharmaceuticals in 1962. 65,66 The primary interest of Schroeder and Triadan in the development of Ledermix paste was based on the use of corticosteroids to control pain and inflammation while the antimicrobial properties at the time were catered for by a formalinbased paste called Asphalin (introduced in 1921). The sole reason for adding the antibiotic component to Ledermix paste was to compensate for what was perceived to be a possible corticoid-induced reduction in the host immune response.…”

Section: (B) Antibioticsmentioning

confidence: 99%

“…Ledermix paste has also been shown to be useful in reducing the incidence of pain following chemomechanical preparation of root canals. 65,80 Dentine acts as a slow release mechanism for triamcinolone to the periodontal tissues which is the probable basis of its long-acting therapeutic effect. 67 Ehrmann et al 80 have shown that Ledermix paste provides greater postoperative pain relief compared to teeth medicated with calcium hydroxide, and this has been confirmed by several other studies.…”

Section: (B) Antibioticsmentioning

confidence: 99%

“…61 Tetracyclines are bacteriostatic rather than bactericidal, and it is well known that yeasts are resistant to tetracyclines. 7,65 Tetracyclines exhibit a level of substantivity due to their ability to form complexes with bivalent and trivalent cations. It is for this same reason that they are deposited in teeth and bones during calcification.…”

Section: (B) Antibioticsmentioning

confidence: 99%

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The use of calcium hydroxide, antibiotics and biocides as antimicrobial medicaments in endodontics

Athanassiadis

Abbott

Walsh

2007

Australian Dental Journal

300

278

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Bacteria have been implicated in the pathogenesis and progression of pulp and periapical diseases. The primary aim of endodontic treatment is to remove as many bacteria as possible from the root canal system and then to create an environment in which any remaining organisms cannot survive. This can only be achieved through the use of a combination of aseptic treatment techniques, chemomechanical preparation of the root canal, antimicrobial irrigating solutions and intracanal medicaments. The choice of which intracanal medicament to use is dependent on having an accurate diagnosis of the condition being treated, as well as a thorough knowledge of the type of organisms likely to be involved and their mechanisms of growth and survival. Since the disease is likely to have been caused by the presence of bacteria within the root canal, the use of an antimicrobial agent is essential. Many medicaments have been used in an attempt to achieve the above aims but no single preparation has been found to be completely predictable or effective. Commonly used medicaments include calcium hydroxide, antibiotics, non-phenolic biocides, phenolic biocides and iodine compounds. Each has advantages and disadvantages, and further research is required to determine which is best suited for root canal infections.Key words: Endodontics, bacteria, antimicrobial, medicaments.Abbreviations and acronyms: Ca(OH) 2 = calcium hydroxide; CFU = colony forming units; CHX = chlorhexidine; CMP = camphorated monochlorophenol; CP = camphorated phenol; IPI = iodine potassium iodide; LPS = lipopolysaccharide; NaOCI = sodium hypochlorite; PEG = polyethyleneglycol; PMCP = paramonochlorophenol; QAC = quaternary ammonium compounds.

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Section: (B) Antibioticsmentioning

confidence: 99%

Section: (B) Antibioticsmentioning

confidence: 99%

Section: (B) Antibioticsmentioning

confidence: 99%

Section: (B) Antibioticsmentioning

confidence: 99%

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The use of calcium hydroxide, antibiotics and biocides as antimicrobial medicaments in endodontics

Athanassiadis

Abbott

Walsh

2007

Australian Dental Journal

300

278

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“…The mechanism of postendodontic pain is complex, but several factors play a role in development of pain including cutting and excavating the pulp tissue, traumatizing the periapical tissue by endodontic instruments and entry of foreign materials into the periapical tissue (4). Medications used for postendodontic pain management include mefenamic acid (4), local corticosteroids (4,15), intramuscular corticosteroids (4) and a combination of aspirin, ibuprofen and opioids (16). Non-steroidal antiinflammatory drugs (NSAIDs) like ibuprofen are the most commonly used analgesics for the management of endodontic pain (17).…”

Section: Introductionmentioning

confidence: 99%

Attitude of Dentists Towards the Administration of Analgesics for Management of Post-Endodontic Pain in Hamadan

Jamshidi¹,

Baghaei²,

Doniavi³

et al. 2014

Avicenna J Dent Res

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Background: Prevention or management of pain is an important objective in root canal treatment. Post-endodontic pain has always been an important concern for patients and clinicians. Informing patients regarding the possibility of postendodontic pain and drug administration for its management can improve their trust in dentists, raise their pain threshold and increase their tendency to seek further dental treatments. Objectives: This study aimed to assess the attitude of Hamadan dentists towards the administration of analgesics for the management of postendodontic pain. Patients and Methods: This descriptive, cross-sectional study was conducted in 2011 in Hamadan city, Iran. Data was collected using a questionnaire including demographic information and questions about administration of analgesics for endodontic patients. All participants filled out the questionnaires anonymously. Collected data was analyzed using SPSS version 16.0 and descriptive statistics. Results: Eighty questionnaires were completed by dentists. Most dentists reported to use ibuprofen mostly to alleviate mild to moderate and severe endodontic pain in healthy individuals. Only 42 dentists (52.5%) used intracanal medicaments to relieve pain. Conclusions:The overall level of knowledge of general dentists in Hamadan city about the prescription of analgesics was satisfactory. Dentists should be aware of the latest advancements in their field and maintain their level of knowledge by regularly participating in continuous education programs and accessing relevant scientific resources.

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Pharmacological Management of Acute Endodontic Pain

Khan

Diogenes

2021

Drugs

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Pain associated with infections of the tooth pulp and periapical tissues is intense and often the most common reason for patients seeking emergency dental care. Effective management of acute dental pain requires a deep understanding of pain mechanisms, which enables accurate diagnosis and definitive treatment. While drugs are only used as an adjunct to definitive dental treatment, a thorough understanding of their mechanism of action and effectiveness enables clinicians to effectively control intra-operative and post-operative pain and prevent persistent pain. This review describes how pain is detected, processed, and perceived. It also provides information on evidence-based strategies on the use of different classes of drugs to effectively manage endodontic pain.

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The effect of triamcinolone with tetracycline on the dental pulp and apical periodontium

Cited by 43 publications

References 17 publications

The use of calcium hydroxide, antibiotics and biocides as antimicrobial medicaments in endodontics

The use of calcium hydroxide, antibiotics and biocides as antimicrobial medicaments in endodontics

Attitude of Dentists Towards the Administration of Analgesics for Management of Post-Endodontic Pain in Hamadan

Pharmacological Management of Acute Endodontic Pain

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