The effect of tumor location on oncologic outcomes in patients with upper urinary tract urothelial carcinoma stratified by pathologic stage

Comparative study of lymph node dissection, and oncological outcomes of laparoscopic and open radical nephroureterectomy for patients with urothelial carcinoma of the upper urinary tract undergoing regional lymph node dissection

“…Regarding the adverse survival impact of the distal ureteral tumor location in pT3/T4 patients, our observation was consistent with previous studies. Tai et al reported that patients with pT3 ureteral tumors had a poorer RFS than those with pT3 renal pelvis tumors (5-year RFS: 50 vs. 71%, respectively, P = 0.047) ( 16 ). Park et al also found that the ureteral tumor location had an adverse prognostic impact only in patients with pT3 disease ( 17 ).…”

Effects of tumor size and location on survival in upper tract urothelial carcinoma after nephroureterectomy

“…[ 6 7 8 ] Furthermore, there is controversy within the literature with regards to the impact of tumor location (renal pelvis vs. ureter) on survival outcomes. Whereas several studies of smaller cohorts appear to indicate that tumor location is predictive of postoperative outcomes,[ 9 10 11 12 ] other groups failed to show such a correlation. [ 13 14 15 ] The analysis of the largest prospective cohort of UTUC patients to date (the UTUC Collaboration) did not find tumor location to be of prognostic import.…”

Survival differences of patients with ureteral versus pelvicalyceal tumours: a systematic review and meta-analysis

“…The 14 studies in this meta-analysis included 14,895 participants [13][14][15][16][17][18][19][20][21][22][23][24][25][26]. The baseline characteristics of the included studies are summarised in Table I study ranged from 133 to 3387 (mean 1064, median 623).…”