The effect of unloading and reloading on the extracellular matrix in skeletal muscle: changes in muscle strength and motor activity

Riso, EM; Ahtikoski, AM; Takala, Tuomo; Seene, Teet

doi:10.5604/20831862.913073

Cited by 3 publications

(1 citation statement)

References 19 publications

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“…Glucocorticoids increased myofibrillar protein degradation in FT muscles, while fibril- and network-forming collagen specific mRNA levels decreased at the same time in FT and ST muscles [ 45 ]. Both the myofibrillar apparatus and the ECM play a crucial role in changes of muscle strength during glucocorticoid administration and following muscle loading [ 70 ].…”

Section: The Preventive Role Of Exercise Therapy On Aging Unloadedmentioning

confidence: 99%

Role of Exercise Therapy in Prevention of Decline in Aging Muscle Function: Glucocorticoid Myopathy and Unloading

Seene

Kaasik

2012

Journal of Aging Research

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Changes in skeletal muscle quantity and quality lead to disability in the aging population. Physiological changes in aging skeletal muscle are associated with a decline in mass, strength, and inability to maintain balance. Glucocorticoids, which are in wide exploitation in various clinical scenarios, lead to the loss of the myofibrillar apparatus, changes in the extracellular matrix, and a decrease in muscle strength and motor activity, particularly in the elderly. Exercise therapy has shown to be a useful tool for the prevention of different diseases, including glucocorticoid myopathy and muscle unloading in the elderly. The purpose of the paper is to discuss the possibilities of using exercise therapy in the prevention of glucocorticoid caused myopathy and unloading in the elderly and to describe relationships between the muscle contractile apparatus and the extracellular matrix in different types of aging muscles.

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Section: The Preventive Role Of Exercise Therapy On Aging Unloadedmentioning

confidence: 99%

Role of Exercise Therapy in Prevention of Decline in Aging Muscle Function: Glucocorticoid Myopathy and Unloading

Seene

Kaasik

2012

Journal of Aging Research

View full text Add to dashboard Cite

show abstract

Review on aging, unloading and reloading: Changes in skeletal muscle quantity and quality

Seene

Kaasik

Riso

2012

Archives of Gerontology and Geriatrics

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Effects of aging on basement membrane of the soleus muscle during recovery following disuse atrophy in rats

Ikegami

Sujino

Koinuma

et al. 2017

Experimental Gerontology

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The effect of unloading and reloading on the extracellular matrix in skeletal muscle: changes in muscle strength and motor activity

Cited by 3 publications

References 19 publications

Role of Exercise Therapy in Prevention of Decline in Aging Muscle Function: Glucocorticoid Myopathy and Unloading

Role of Exercise Therapy in Prevention of Decline in Aging Muscle Function: Glucocorticoid Myopathy and Unloading

Review on aging, unloading and reloading: Changes in skeletal muscle quantity and quality

Effects of aging on basement membrane of the soleus muscle during recovery following disuse atrophy in rats

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