1966
DOI: 10.1016/0002-8703(66)90177-3
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The effect of upright posture on right ventricular volumes in patients with and without heart failure

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Cited by 38 publications
(11 citation statements)
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“…In addition, we have recently studied the effects of tilting into the upright position on a separate group of subjects without heart disease and patients with heart failure. 33 The recumbent right ventricular volumes in the normal and heart failure subjects were comparable to the values reported in this study. On upright tilting, however, the EDV fell in the normal subjects and remained unchanged in the patients with heart failure.…”
Section: Restsupporting
confidence: 85%
“…In addition, we have recently studied the effects of tilting into the upright position on a separate group of subjects without heart disease and patients with heart failure. 33 The recumbent right ventricular volumes in the normal and heart failure subjects were comparable to the values reported in this study. On upright tilting, however, the EDV fell in the normal subjects and remained unchanged in the patients with heart failure.…”
Section: Restsupporting
confidence: 85%
“…The observations on patients with chronic congestive heart failure re ported here are in agreement with more fragmentary earlier studies by Howard and Leathart [7], who in 1951 first reported patients with left ventri cular failure who increased their pulse pressure upon upright tilt, without changing their heart rate, as well as with several more recent studies of the hemodynamic effects of orthostatic stress upon patients in heart failure [3,4,11,13]. Together with these earlier studies, the present investigations establish that tolerance of orthostatic stress is increased in chronic con gestive heart failure, resulting in excellent tolerance of acute depletion of plasma volume as well as chronic immobilization, and suggest that increased circulatory blood volume, increased sympathetic tone and possibly chronic hypoxia [9] play a role in this tolerance.…”
Section: Discussionsupporting
confidence: 92%
“…This produces diminished right and left ventricular filling pressures and a fall in stroke volume [12]. Normal subjects maintain mean blood pressure in response to upright tilting by rising diastolic blood pressure and heart rate, with little or no change in systolic blood pressure [7].…”
Section: Discussionmentioning
confidence: 99%