The effect of water and shampooing on the efficacy of a pyriprole 12.5% topical solution against brown dog tick (Rhipicephalus sanguineus) and cat flea (Ctenocephalides felis) infestations on dogs

Schuele, G.; Barnett, S.; Bapst, B.; Cavaliero, T.; Luempert, Louis G.; Strehlau, G.; Young, D. R.; Moran, C.; Junquera, P.

doi:10.1016/j.vetpar.2007.10.009

Cited by 9 publications

(4 citation statements)

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“…Similar studies have been conducted by Schuele et al [29] in which the effect of shampooing or immersion in water on the efficacy of a spot-on formulation of pyriprole against C. felis felis and R. sanguineus was evaluated. In the one study efficacy against C. felis felis and R. sanguineus remained above 99% during the 30 days of the study.…”

Section: Resultsmentioning

confidence: 72%

“…Spot-on formulations of pyriprole as well as a combination of cyphenothrin and pyriproxyfen, have proved to be effective against fleas and ticks for 30 to 35 days after their application [29,33]. Efficacy against re-infestation with R. sanguineus , lasting for at least 170 days has been reported for a collar impregnated with a slow-release formulation of flumethrin and propoxur [34].…”

Section: Discussionmentioning

confidence: 99%

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Efficacy of an imidacloprid/flumethrin collar against fleas, ticks, mites and lice on dogs

et al. 2012

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BackgroundThe studies reported here were conducted to ascertain the efficacy of imidacloprid/flumethrin incorporated in a slow-release matrix collar, against infestations of dogs by fleas, ticks, mites and lice. Efficacy was evaluated against the flea Ctenocephalides felis felis, the ticks Rhipicephalus sanguineus, Ixodes ricinus, Ixodes scapularis, Dermacentor reticulatus and Dermacentor variabilis, the mite Sarcoptes scabiei and the biting louse Trichodectes canis.MethodsGroups of collar-treated dogs (n = 7–10) were infested with fleas and/or ticks at monthly intervals at least, over a period of up to 8 months. Efficacy against fleas was evaluated 24 to 48 h after treatment and 24 h after each re-infestation. Efficacy against ticks was evaluated at 48 h (acaricidal), 6 h (repellent) and 48 h (sustained) after infestation. The effect of regular shampooing or immersion in water on the efficacy of the collars was also tested. Efficacy against flea larvae was assessed by incubating blanket samples after dog contact with viable flea eggs. Effectiveness against lice and mites was evaluated after treatment of naturally infested animals. With the exception of the mites, efficacy was calculated by comparison with untreated negative control groups.ResultsEfficacy against fleas (24 h) generally exceeded 95%, and against flea larvae it exceeded 99% for 8 months. Sustained acaricidal (48 h) efficacy, covering a period of 8 months was 100% against I. ricinus, starting 2 days after treatment (in vivo), and 100% against I. scapularis (in vitro), above 97% against R. sanguineus, generally above 97% against D. reticulatus and above 90% for D. variabilis.Repellent (6 h) efficacy 2 days after treatment and continuing for 8 months was consistently 100% against I. ricinus, and above 90% against R. sanguineus.Regular shampooing affected efficacy against fleas and ticks to a lesser extent than regular immersion in water.The collars eliminated Trichodectes canis within 2 days and Sarcoptes scabiei within 3 months.ConclusionThe rapid insecticidal and acaricidal properties of the medicated collars against newly-acquired infestations of fleas and ticks and their sustained high levels of preventive efficacy have been clearly shown. Consequently they have the potential to prevent the transmission of vector-borne diseases and other conditions directly associated with infestation throughout an entire season of parasite abundance.

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Section: Resultsmentioning

confidence: 72%

Section: Discussionmentioning

confidence: 99%

Efficacy of an imidacloprid/flumethrin collar against fleas, ticks, mites and lice on dogs

et al. 2012

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“…Topical applications of pyriprole to dogs provided >95% kill for 35 days and similar results for animals washed once each week [ 383 ]. A topical application of pyriprole on dogs prevented fleas from laying eggs for at least 30 days [ 384 ].…”

Section: Pest Managementmentioning

confidence: 92%

“…A topical application of 20 mg/kg or 40 mg/kg metaflumizone/amitraz to dogs provided >95% kill of fleas for at least 35 days [ 338 ]. A single spot on application of metaflumizone on cats provided >90% kill of fleas for up to 7 weeks [ 383 ]. In another study, metaflumizone applied to cats (40 mg/kg) provided 97.4% kill of fleas for 4 weeks compared with 71.3% kill for fipronil/methoprene [ 340 ].…”

Section: Pest Managementmentioning

confidence: 99%

The Biology and Ecology of Cat Fleas and Advancements in Their Pest Management: A Review

Rust

2017

Insects

114

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The cat flea Ctenocephalides felis felis (Bouché) is the most important ectoparasite of domestic cats and dogs worldwide. It has been two decades since the last comprehensive review concerning the biology and ecology of C. f. felis and its management. Since then there have been major advances in our understanding of the diseases associated with C. f. felis and their implications for humans and their pets. Two rickettsial diseases, flea-borne spotted fever and murine typhus, have been identified in domestic animal populations and cat fleas. Cat fleas are the primary vector of Bartonella henselae (cat scratch fever) with the spread of the bacteria when flea feces are scratched in to bites or wounds. Flea allergic dermatitis (FAD) common in dogs and cats has been successfully treated and tapeworm infestations prevented with a number of new products being used to control fleas. There has been a continuous development of new products with novel chemistries that have focused on increased convenience and the control of fleas and other arthropod ectoparasites. The possibility of feral animals serving as potential reservoirs for flea infestations has taken on additional importance because of the lack of effective environmental controls in recent years. Physiological insecticide resistance in C. f. felis continues to be of concern, especially because pyrethroid resistance now appears to be more widespread. In spite of their broad use since 1994, there is little evidence that resistance has developed to many of the on-animal or oral treatments such as fipronil, imidacloprid or lufenuron. Reports of the perceived lack of performance of some of the new on-animal therapies have been attributed to compliance issues and their misuse. Consequentially, there is a continuing need for consumer awareness of products registered for cats and dogs and their safety.

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Discovery of pyridine-based agrochemicals by using Intermediate Derivatization Methods

Guan

Liu²,

Sun³

et al. 2016

Bioorganic & Medicinal Chemistry

228

106

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The effect of water and shampooing on the efficacy of a pyriprole 12.5% topical solution against brown dog tick (Rhipicephalus sanguineus) and cat flea (Ctenocephalides felis) infestations on dogs

Cited by 9 publications

References 11 publications

Efficacy of an imidacloprid/flumethrin collar against fleas, ticks, mites and lice on dogs

Efficacy of an imidacloprid/flumethrin collar against fleas, ticks, mites and lice on dogs

The Biology and Ecology of Cat Fleas and Advancements in Their Pest Management: A Review

Discovery of pyridine-based agrochemicals by using Intermediate Derivatization Methods

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