The Effect of Zinc Supplementation on Linear Growth, Body Composition, and Growth Factors in Preterm Infants

Díaz-Gómez, N. Marta; Doménech, E; Barroso, Flora; Castells, Silvia; Cortabarría, C; Jiménez, Alejandro

doi:10.1542/peds.111.5.1002

Cited by 89 publications

(120 citation statements)

References 24 publications

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“…The lack of effect on weight in their study may have been due to factors like low sample size (N=52), formula feed and the fact that their study cohort comprised of VLBW infants. Similar findings were also noted by Gomez et al 3 in his study of 36 preterm infants. The authors found significant effect of zinc supplementation on length but not on weight gain.…”

Section: Discussionsupporting

confidence: 91%

“…Zinc deficiency in infants has been shown to have an adverse impact on growth and immunity in many studies 2 . Several studies have demonstrated the benefit of zinc supplementation in low birth infants with regard to growth and prevention of infections [2][3][4][5][6][7] However, some studies have shown marginal or no effect 8 , It is with this view that the present study is undertaking to evaluate the effectiveness of zinc supplementation in LBW infants in our set up.…”

Section: Introductionmentioning

confidence: 99%

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To Study the Role of Zinc Supplementation on Growth of Low Birth Weight Infants

Sonawane¹,

Patil²,

Gulati³

et al. 2014

mvpjms

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This was a randomized controlled trial undertaken to study the role of zinc supplementation on growth of low birth weight infants (b.wt≤2500 gm). Out of 120 LBW infants, 23 were excluded due to loss of follow up. The remaining 97 LBW eligible neonates were randomized in to 2 group (zinc & control group), zinc group were given zinc supplementation at a dose of 2 mg/kg/day for 8 weeks from enrollment. They were then followed up every 4 weeks up to 8 weeks. At each visit, detail anthropometry including e weight, length, and head circumference were recorded at each visit. The infants in the zinc group had significantly higher weight gain (p<0.000), length gain (p<0.000), linear growth velocity and head circumference at 8 weeks. We concluded that zinc supplementation at 2 mg/kg/day for 8 weeks in LBW infants improves their growth during infancy.

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Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

To Study the Role of Zinc Supplementation on Growth of Low Birth Weight Infants

Sonawane¹,

Patil²,

Gulati³

et al. 2014

mvpjms

View full text Add to dashboard Cite

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“…Of the 3 studies conducted in developed countries (Spain and Canada), 2 studies among preterm infants showed positive effect on plasma zinc concentrations and linear growth(3,4) and 1 on LBW infants showed no effect(5). However, no significant effect on weight gain was VOLUME 47 __ OCTOBER 17, 2010 SAZAWAL AND BLACK EFFECT OF ORAL ZINC SUPPLEMENTATION observed in any of these studies (3)(4)(5). The available evidence for the effect of zinc supplementation on growth among low birth weight infants from developing countries setting is from India (2 studies)(6,7), Bangladesh (1 study)(8), Chile (1 study) (9) and Brazil (1 study) (10).…”

Section: E D I T O R I a L E D I T O R I A L E D I T O R I A L E D I mentioning

confidence: 87%

Effect of oral zinc supplementation on the growth of preterm infants

Sazawal

Black

2010

Indian Pediatr

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“…Zinc plays important roles in various physiologic functions in growth, development, and sexual maturity in males [16,21]. Zinc also plays biological roles in antioxidant properties, lipid metabolism, insulin resistance, immune response, sperm physiology and hepatic injury [3,26,34,39].…”

Section: Introductionmentioning

confidence: 99%

Antioxidative Activity of Zinc-Enriched Saccharomyces cerevisiae FF-10 in In vitro Model Systems

Young¹,

Park²,

Ahn³

et al. 2009

Journal of Life Science

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Zinc is an essential trace element for human and plays an important biological role in antioxidant properties. We have been reported that zinc-enriched S. cerevisiae FF-10 contained 392 mg% in the YM basal and 3,193 mg% in the YM optimal medium. Antioxidative activity of FF-10 was tested in vitro models by DPPH (α,α'-diphenyl-β-picrylhydrazyl) radical scavenging activity and lipid peroxidation using linoleic acid (LA) and rat liver homogenate. DPPH radical scavenging activity was higher in the cell-free extract of FF-10 cultured in the YM optimal medium (YMOM) than that in the YM basal medium (YMBM). The inhibition activity of lipid peroxidation using rat liver homogenate was shown in the following order: BHT ＞ YMOM ＞ YMBM and these values were dose dependently. The lipid peroxidation of the control mixture by ferric thiocyanate and TBA methods using LA was increased rapidly as typical peroxidation curve of LA from one day and the antioxidation activity of the cell free extracts by cultivating FF-10 in the YMOM were higher than that of the YMBM. Result of this study indicate that the cell-free extracts containing a high intercellular zinc of S. cerevisiae FF-10 cultured in YMOM showed strong antioxidation capacities in DPPH radical scavenging activity and lipid peroxidation using LA and rat liver homogenate.

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The Effect of Zinc Supplementation on Linear Growth, Body Composition, and Growth Factors in Preterm Infants

Abstract: Zinc supplementation has a positive effect on linear growth in premature infants.

Cited by 89 publications

References 24 publications

To Study the Role of Zinc Supplementation on Growth of Low Birth Weight Infants

To Study the Role of Zinc Supplementation on Growth of Low Birth Weight Infants

Effect of oral zinc supplementation on the growth of preterm infants

Antioxidative Activity of Zinc-Enriched Saccharomyces cerevisiae FF-10 in In vitro Model Systems

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