The Effectiveness and Safety of Transabdominal Oocyte Pick-up Using a Vaginal Ultrasound Probe in Patients with Endometrioma Undergoing Oocyte Cryopreservation

Abstract

Background This retrospective cohort study aimed to assess the safety and effectiveness of transabdominal oocyte pick-up using a vaginal ultrasound probe in single women with endometrioma undergoing oocyte cryopreservation (OC). Methods Twenty single women with endometrioma who underwent transabdominal oocyte pick-up using a vaginal ultrasound probe for the purpose of oocyte cryopreservation were included. Primary outcome measures were number of oocytes retrieved, mature oocytes frozen, a modified follicle to oocyte index (FOI), and complication rates. Results The mean age of patients was 33.1±5.8, mean diameter of the endometrioma was 57.9±33.7 mm, mean antral follicle count was 6.3±3.4, mean serum AMH was 0.78±0.55 ng/ml, and mean day 3 serum FSH and estradiol were 9.2±2.3 IU/ml and 57.8±36.5 pg/ml, respectively. The mean duration of stimulation was 9.7±2.3 days, total gonadotropin consumption was 2195±909 units, and duration of the procedure was 9.9±4.2 min. The mean number of oocytes retrieved, MII oocytes frozen, and mFOI were 6.1±3.6, 4.8±2.9, 0.93±0.19 respectively. Conclusions Endometrioma was ruptured in four patients, and only one patient was temporarily hospitalized for six hours for severe pelvic pain. Transabdominal oocyte retrieval using a vaginal probe is safe and effective technique in patients with endometrioma undergoing OC.