The Effectiveness and Safety of Transabdominal Oocyte Pick up Using a Vaginal Ultrasound Probe in Patients with Endometrioma Undergoing Oocyte Cryopreservation

Abstract

To assess whether transabdominal oocyte pick up is safe and effective in single patients with endometrioma undergoing IVF for the purpose of oocyte cryopreservation. Materials and Methods: In this retrospective cohort study 13 virgin patients with endometrioma who underwent transabdominal oocyte pick-up for the purpose of oocyte cryopreservation was analyzed. Demographic characteristics, and hormonal assessment including AMH, day 3 serum FSH, LH, estradiol and progesterone levels, and antral follicle counts were recorded. Primary outcome measures were number of oocytes retrieved, metaphase 2 oocytes frozen, follicle oocyte index, and complication rates, while secondary outcome measures were duration of stimulation, cumulative gonadotropin dose, and duration of the procedure. Results: The mean age of patients was 32,78,5. The mean diameter of the endometrioma was 48,123,6 mm, antral follicle count was 6,022,92, serum AMH was 0.620.32 ng/ml, and day 3 serum FSH and estradiol were 9,32,4 IU/ml and 60,028,6 pg/ml respectively. The mean duration of stimulation was 8,51,98 days, cumulative gonadotropin consumption was 1659546 units, and duration of the procedure was 8.33.9 min. The mean number of oocytes retrieved was 5,53.1, oocytes frozen was 4,152.23, and mean modified follicle oocyte index was 0,930,17. No major complication occurred in any of the patients; however, one patient was temporarily hospitalized for six hours for severe pelvic pain. Conclusions: Transabdominal oocyte pick up is safe and effective procedure in single patients with endometrioma undergoing IVF for the purpose of oocyte cryopreservation.