The effectiveness of 10% chlorhexidine varnish treatment on dental caries incidence in adults with dry mouth

Banting, David W.; Papas, Athena; Clark, D. Christopher; Proskin, Howard M.; Schultz, Myron G.; Perry, Ross

doi:10.1111/j.1741-2358.2000.00067.x

Cited by 69 publications

(53 citation statements)

References 35 publications

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“…The median (25th/75th percentiles) follow-up time was 15 (12/24) mo. Eleven studies investigated dentifrices (Jensen and Kohout 1988;Banoczy and Nemes 1991;Baysan et al 2001;Paraskevas et al 2004;Papas et al 2007;Papas et al 2008;Vered et al 2009;Ekstrand et al 2013;Hu et al 2013;Souza et al 2013;Srinivasan et al 2013), 10 rinses (Ripa et al 1987;Banoczy and Nemes 1991;Ravald and Birkhed 1992;Wallace et al 1993;Fure et al 1998;Powell et al 1999;Paraskevas et al 2004;Wyatt and MacEntee 2004;Petersson et al 2007;Wyatt et al 2007), 8 varnishes (Schaeken et al 1991;Ravald and Birkhed 1992;Powell et al 1999;Banting et al 2000;Baca et al 2009;Fure and Lingstrom 2009;Tan et al 2010;Zhang et al 2013), 3 (fluoride) solutions (Fure and Lingstrom 2009;Tan et al 2010;Zhang et al 2013), 3 gels (Ravald and Birkhed 1992;DePaola 1993;Wallace et al 1993), 2 ozone applications (Holmes 2003;Baysan and Lynch 2007), and 1 preventive dental regimes (Mojon et al 1998). Eleven studies investigated both initiation of RCLs and the change of RCLs, 11 analyzed the change of RCLs, and 8 studied initiation of RCLs ...…”

Section: Resultsmentioning

confidence: 99%

Systematic Review on Noninvasive Treatment of Root Caries Lesions

2014

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The present systematic review critically summarizes results of clinical studies investigating chemical agents to reduce initiation or inactivation of root caries lesions (RCLs). Outcomes were DMFRS/DFRS (decayed, missing, filled root surfaces), surface texture (hard/soft), and/or RCI (root caries index). Three electronic databases were screened for studies from 1947 to 2014. Cross-referencing was used to further identify articles. Article selection and data abstraction were done in duplicate. Languages were restricted to English and German. Mean differences (MD) were calculated for changes in DMFRS/DFRS. Risk ratios (RR) were calculated for changes in surface texture and RCI in a random effects model. Thirty-four articles with 1 or more agents were included; they reported 30 studies with 10,136 patients who were 20 to 101 y old; and they analyzed 28 chemical agents (alone or in combination). Eleven studies investigated dentifrices, 10 rinses, 8 varnishes, 3 solutions, 3 gels, and 2 ozone applications. Meta-analyses revealed that dentifrices containing 5,000 ppm Regular use of dentifrices containing 5,000 ppm F -and quarterly professionally applied CHX or SDF varnishes seem to be efficacious to decrease progression and initiation of root caries, respectively. However, this conclusion is based on only very few well-conducted randomized controlled trials.

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Section: Resultsmentioning

confidence: 99%

Systematic Review on Noninvasive Treatment of Root Caries Lesions

2014

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“…However, gingival recession caused by normal aging, periodontal disease or traumatic toothbrushing habits renders the retained dentition susceptible to root surface caries [2][3][4] . Additionally, the risk for root surface caries is further increased with reduced salivary flow or xerostomia due to aging or medication 5) . According to the literature, the prevalence of root surface caries amongst noninstitutionalized people over the age of 60 years in Western countries and Japan is higher than 50% 4) .…”

Section: Introductionmentioning

confidence: 99%

Effects of a coating resin containing S-PRG filler to prevent demineralization of root surfaces

Imazato

Chen

et al. 2012

Dent. Mater. J.

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The purpose of this study was to evaluate the ability of a coating material containing the surface pre-reacted glass-ionomer (S-PRG) filler to protect the root from demineralization in vitro. The proprietary coating resin containing the S-PRG filler (PRG Barrier Coat) was applied to human root dentin and immersed in acid buffer at pH 4.5 for 3 d. Demineralization was evaluated by micro-CT scanning and the dentin-material interface observed by scanning electron microscopy. The ability of the coating resin to modify acid production by Streptococcus mutans was investigated by monitoring pH using an ion-sensitive field-effect transistor pH electrode. Application of PRG Barrier Coat produced a coating layer with the thickness of approximately 200 µm and completely inhibited demineralization. The bacteria-induced pH fall at the material surface was significantly inhibited. We conclude that S-PRG fillercontaining coating resin may be an effective material for protecting exposed root from both chemical and biological challenges. Keywords: Resin coating, Root caries, Demineralization, S-PRGThe second and third authors contributed equally to this work.

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“…Because cementum has half as much mineral as enamel by weight, demineralization on the root surface is approximately twice as rapid as that on enamel and can occur at a higher pH 3) . Additionally, root dentine surfaces may even present a high risk to caries development 4) due to a low salivary flow, which is frequently found in elderly as a side-effect of daily use of medicines 5) . Various treatment modalities have been proposed for the management of root caries, including the improvement of oral conditions for oral hygiene, topical application of remineralization agents and antimicrobial regimen 6) , and coating or sealing by resin-based materials 7) .…”

Section: Introductionmentioning

confidence: 99%

Evaluation of resin infiltration on demineralized root surface: An <i>in vitro</i> study

Zhou

Matin

Shimada

et al. 2017

Dental Materials Journal

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The aim of this study was to evaluate the effect of resin infiltration on root caries induced by Streptococcus mutans biofilms. Human premolar specimens were divided to 5 groups: negative control (NC), Clearfil SE Bond (SEB), Icon-etch120s+Icon-infiltrant (HA120), Icon-etch10s+Icon-infiltrant (HA10) and K-etchant10s+Icon-infiltrant (PA10). The resin penetration was observed by fluorescent microscope. Biofilm-induced demineralization was conducted again and observed by swept-source optical coherence tomography and confocal laser scanning microscope. The maximum resin penetration depth (PDmax), lesion depth increase (∆LD), frequency of cervical enamel loss and dentinoenamel junction separation length were measured and statistically analyzed. HA120 showed 138.00±49.25 µm PDmax that was significantly larger than PA10 and SEB (p<0.05). SEB created 136.58±64.73 µm coating layers. HA120 and SEB showed significantly lower ∆LD than NC (p<0.05). Resin infiltration with 120s-HCl pretreatment has got a good penetration ability and preventive effect on root caries, however, an additional risk factor of cervical enamel loss was identified.

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The effectiveness of 10% chlorhexidine varnish treatment on dental caries incidence in adults with dry mouth

Abstract: The difference between the 10% chlorhexidine varnish and placebo treatments is considered to be highly clinically significant for root caries increment (41% reduction) and for total caries increment (25% reduction) but only for coronal caries increment (14%).

Cited by 69 publications

References 35 publications

Systematic Review on Noninvasive Treatment of Root Caries Lesions

Systematic Review on Noninvasive Treatment of Root Caries Lesions

Effects of a coating resin containing S-PRG filler to prevent demineralization of root surfaces

Evaluation of resin infiltration on demineralized root surface: An <i>in vitro</i> study

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