The Effectiveness of Mindfulness-Integrated Cognitive Behavior Therapy on Depression, Anxiety, and Stress in Females with Multiple Sclerosis: A Single Blind Randomized Controlled Trial

Bahrani, Shima; Zargar, Fatemeh; Yousefipour, Gholamali; Akbari, Hossein

doi:10.5812/ircmj.44566

Cited by 26 publications

(19 citation statements)

References 39 publications

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“…Twelve RCTs were identified as eligible for inclusion in the systematic review. [21][22][23][24][25][26][27][28][29][30][31][32] However, only eight studies reported endpoint data that could be included in the meta-analysis. 21-24 28-30 32 (figure 1).…”

Section: Resultsmentioning

confidence: 99%

“…The largest overall effects were reported for MiCBT, 23 SMD 0.80 (0.48-1.12), I 2 =0%, but this was a pre-post-RCT (n=56), vs usual care. Overall effects for MBCT vs usual care came from a small study 28 (n=40), where SMD was 0.78 (0.45, 1.11), I 2 =0%.…”

Section: Outcomes By Intervention Typementioning

confidence: 87%

“…Five studies took place in Iran, 23 25-27 29 three in the UK, 22 28 31 two in Italy, 24 32 one each in Switzerland 30 and the USA. 21 Six studies reported assessing a MBI against usual care, 22 23 28-31 in three this was not specified, [22][23][24] while three used an active comparator (psychoeducation control). 21 24 32 Six studies were powered.…”

Section: Study Characteristicsmentioning

confidence: 99%

“…Five studies used mindfulness-based stress reduction (MBSR), 21 22 29 30 32 two based on MBSR, 24 27 three mindfulness-based cognitive therapy (MBCT), 25 26 28 one mindfulness-integrated CBT (MiCBT) 23 and one mindfulness of movement. 31 Six studies reported on participant materials.…”

Section: Intervention Characteristicsmentioning

confidence: 99%

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Mindfulness-based interventions for mental well-being among people with multiple sclerosis: a systematic review and meta-analysis of randomised controlled trials

Simpson

Ramparsad

et al. 2019

J Neurol Neurosurg Psychiatry

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Objective impairment of mental well-being (anxiety, depression, stress) is common among people with multiple sclerosis (PwMS). Treatment options are limited, particularly for anxiety. The aim of this study was to update our previous systematic review (2014) and evaluate via meta-analysis the efficacy of mindfulnessbased interventions (MBis) for improving mental wellbeing in PwMS. Methods Systematic searches for eligible randomised controlled trials (RCTs) were carried out in seven major databases (November 2017, July 2018), using medical subject headings and key words. Studies were screened, data extracted, quality appraised and analysed by two independent reviewers, using predefined criteria. Study quality was assessed using the Cochrane Collaboration risk of bias tool. Mental well-being was the primary outcome. Random effects model meta-analysis was performed, with effect size reported as standardised mean difference (SMD). results Twelve RCTs including 744 PwMS were eligible for inclusion in the systematic review, eight had data extractable for meta-analysis; n=635. ethnicity, socioeconomic status, comorbidity and disability were inconsistently reported. MBis varied from manualised to tailored versions, lasting 6-9 weeks, delivered individually and via groups, both in person and online. Overall SMD for mental well-being (eight studies) was 0.40 (0.28-0.53), p<0.01, i 2 =28%; against active comparators only (three studies) SMD was 0.17 (0.01-0.32), p<0.05, i 2 =0%. Only three adverse events were reported. Conclusions MBis are effective at improving mental well-being in PwMS. More research is needed regarding optimal delivery method, cost-effectiveness and comparative-effectiveness. PrOsPErO registration number CRD42018093171.search strategy

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Section: Resultsmentioning

confidence: 99%

Section: Outcomes By Intervention Typementioning

confidence: 87%

Section: Study Characteristicsmentioning

confidence: 99%

Section: Intervention Characteristicsmentioning

confidence: 99%

See 2 more Smart Citations

Mindfulness-based interventions for mental well-being among people with multiple sclerosis: a systematic review and meta-analysis of randomised controlled trials

Simpson

Ramparsad

et al. 2019

J Neurol Neurosurg Psychiatry

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“…Prenatal education, as the most common psychological intervention for pregnant women in China, cannot actively target mental health, for example, by reducing depressive and anxious symptoms . Numerous studies have examined the effectiveness of psychological intervention programs, including cognitive behavioral therapy, interpersonal psychotherapy, and mindfulness interventions . In particular, the mindfulness‐based interventions have shown promise for treating or preventing diverse psychological problems, as well as for relieving pain and improving well‐being .…”

Section: Introductionmentioning

confidence: 99%

Effects of an Online Mindfulness Intervention Focusing on Attention Monitoring and Acceptance in Pregnant Women: A Randomized Controlled Trial

Yang¹,

Jia²,

Sun³

et al. 2019

J Midwife Womens Health

153

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Introduction Attention monitoring and acceptance underlie the effects of mindfulness meditation. This study tested the feasibility and acceptability of an online mindfulness intervention for pregnant women as an approach to reduce depressive and anxious symptoms. Method We developed an 8‐week mindfulness intervention program that trained participants to monitor their internal and external experiences in an accepting way. The mindfulness course was based on the Wechat platform. This study was conducted in a women's hospital in China. A total of 123 women with scores on the Generalized Anxiety Disorder Scale and Patient Health Questionnaire suggesting mild or moderate symptoms of depression and anxiety were recruited from the outpatient department between April and June 2018. The participants were randomized to receive the mindfulness intervention or routine prenatal care. The Generalized Anxiety Disorder Scale, the Patient Health Questionnaire, and the Five Facets of Mindfulness Questionnaire were used to evaluate the levels of anxiety, depression, and mindfulness, respectively, before and after the intervention. Results Of the 123 women enrolled in this study, 10 in the intervention group and 11 in the control group did not complete the intervention. The retention rate and feedback suggested that the mindfulness intervention was feasible and acceptable among pregnant women. Participants in the intervention group showed greater declines in depressive and anxious symptoms compared with those in the control group, as well a significant improvement in mindfulness skills (eg, attention monitoring and acceptance). Discussion These results suggest that an online mindfulness intervention may be a promising technique to help women use mindfulness skills to reduce depressive and anxious symptoms. The mindfulness intervention could constitute part of the psychological care provided to pregnant women.

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Principles of MiCBT

2018

The Clinical Handbook of Mindfulness‐integrated Cognitive Behavior Therapy

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The Effectiveness of Mindfulness-Integrated Cognitive Behavior Therapy on Depression, Anxiety, and Stress in Females with Multiple Sclerosis: A Single Blind Randomized Controlled Trial

Cited by 26 publications

References 39 publications

Mindfulness-based interventions for mental well-being among people with multiple sclerosis: a systematic review and meta-analysis of randomised controlled trials

Mindfulness-based interventions for mental well-being among people with multiple sclerosis: a systematic review and meta-analysis of randomised controlled trials

Effects of an Online Mindfulness Intervention Focusing on Attention Monitoring and Acceptance in Pregnant Women: A Randomized Controlled Trial

Principles of MiCBT

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