The effectiveness of postmortem multidetector computed tomography in the detection of fatal findings related to cause of non-traumatic death in the emergency department

Takahashi, Nobukazu; Higuchi, Tetsuya; Shiotani, Motoi; Hirose, Yasuo; Shibuya, Hiroyuki; Yamanouchi, Haruo; Hashidate, Hideki; Funayama, Kazuhisa

doi:10.1007/s00330-011-2248-6

Cited by 56 publications

(26 citation statements)

References 32 publications

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“…[1][2][3][4][5][6][7] Postmortem magnetic resonance (PMMR) imaging has shown that MR signals and image contrast change after death. 8 -10 Optimization of parameters for PMMR imaging and accurate interpretation of imaging findings require analyses of quantified data.…”

Section: Introductionmentioning

confidence: 99%

Cerebral Relaxation Times from Postmortem MR Imaging of Adults

et al. 2015

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Purpose: We measured T 1 and T 2 values of cerebral postmortem magnetic resonance (PMMR) imaging and compared the data of cadavers with that of living human subjects.Materials and Methods: We performed PMMR imaging of the brains of 30 adults (22 men, 8 women; mean age, 58.2 years) whose deaths were for reasons other than brain injury or disease at a mean of 29.4 hours after death. Before imaging, the bodies were kept in cold storage at 4°C (mean rectal temperature, 15.6°C). We measured T 1 and T 2 values in the brain bilaterally at 5 sites (bilateral caudate nucleus, putamen, thalamus and gray matter and white matter of the frontal lobe) and compared the data of PMMR imaging with that from MR imaging of the corresponding sites in 24 healthy volunteers (9 men, 15 women; mean age, 51.8 years). We also investigated the influence of body temperature on T 1 and T 2 values.Results: Compared with MR imaging findings in the living subjects, PMMR imaging showed significantly shorter T 1 values in the caudate nucleus, putamen, thalamus and gray matter and white matter of the frontal lobe and significantly longer T 2 values in the gray matter and white matter of the frontal lobe; T 2 values in the caudate nucleus, putamen, and thalamus showed no such differences. T 1 values correlated significantly with body temperature in all 5 brain sites measured, but T 2 values did not.Conclusion: Compared with findings of cerebral MR imaging in living adult subjects, those of PMMR imaging tended to demonstrate shorter T 1 values and longer T 2 values. We attribute this to increased water content of tissue, reduced pH, and reduced body temperature after death.

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Section: Introductionmentioning

confidence: 99%

Cerebral Relaxation Times from Postmortem MR Imaging of Adults

et al. 2015

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“…However, in countries with a low autopsy rate, such as Japan, many causes of death are diagnosed by ante-mortem clinical presentation and post-mortem examinations without PMCT or autopsy [4,8]. Comparison of ante-mortem clinical presentation and postmortem examinations with PMCT results is useful for determining whether PMCT examinations are necessary in such countries.…”

Section: Discussionmentioning

confidence: 97%

Can ruptured abdominal aortic aneurysm be accurately diagnosed as the cause of death without postmortem computed tomography when autopsies cannot be performed?

Makino

Yamamoto²,

Shiotani

et al. 2015

Forensic Science International

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“…In Japan and other nations that have low autopsy rates, PMCT is used more widely to diagnose causes of death, as discussed in several previous articles [1,[10][11][12]. These studies, however, have generally had low numbers of cadavers or have been limited to natural deaths.…”

Section: Introductionmentioning

confidence: 96%

Diagnosable and non-diagnosable causes of death by postmortem computed tomography: A review of 339 forensic cases

et al. 2012

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The effectiveness of postmortem multidetector computed tomography in the detection of fatal findings related to cause of non-traumatic death in the emergency department

Abstract: PMMDCT is a feasible tool for detecting morphological fatal findings in non-traumatic death in ED. It is important to know the ability and limitation of PMMDCT.

Cited by 56 publications

References 32 publications

Cerebral Relaxation Times from Postmortem MR Imaging of Adults

Cerebral Relaxation Times from Postmortem MR Imaging of Adults

Can ruptured abdominal aortic aneurysm be accurately diagnosed as the cause of death without postmortem computed tomography when autopsies cannot be performed?

Diagnosable and non-diagnosable causes of death by postmortem computed tomography: A review of 339 forensic cases

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