The effectiveness of pressure garment therapy for the prevention of abnormal scarring after burn injury: a meta-analysis

Anzarut, Alexander; Olson, Jaret; Singh, Pushpa; Rowe, Brian H.; Tredget, Edward E.

doi:10.1016/j.bjps.2007.10.052

Cited by 200 publications

(130 citation statements)

References 31 publications

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“…Different studies have shown up to 90% improvement of keloid scars after using silicon occlusive dressings. 17 Although these kinds of dressings are commonly used to decrease the incidence rate of keloid and hypertrophic scars after surgical procedures, 20 complete resolution has not been reported. 1,18 Onion Extract and Heparin Gel 12 The exact mechanism by which onion extract reduces scar formation is still poorly understood.…”

Section: Silicone Gel Sheetingmentioning

confidence: 99%

Novel Insights on Understanding of Keloid Scar: Article Review

Mari

Alsabri

Tabal

et al. 2015

Journal of the American College of Clinical Wound Specialists

123

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Keloid scar, dermal benign fibro-proliferative growth that extends outside the original wound and invades adjacent dermal tissue due to extensive production of extracellular matrix, especially collagen, which caused by over expression of cytokines and growth factors. Although many attempts were made to understand the exact pathophysiology and the molecular abnormalities, the pathogenesis of keloid scar is yet to be determined. Even though there are several treatment options for keloid scars include combination of medical and surgical therapies like combination of surgical removal followed by cryotherapy or intralesional steroid therapy, the reoccurrence rate is still high despite the present treatment. In this review, PubMed, clinical key and Wright State Library web site have been used to investigate any update regarding Keloid disease. We used Keloid, scar formation, hypertrophic scar and collagen as key words. More than 40 articles have been reviewed. This paper reviews literature about keloid scar formation mechanism, the most recent therapeutic options including the ones under research.

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Section: Silicone Gel Sheetingmentioning

confidence: 99%

Novel Insights on Understanding of Keloid Scar: Article Review

Mari

Alsabri

Tabal

et al. 2015

Journal of the American College of Clinical Wound Specialists

123

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“…This was confirmed in 2012 through a survey of American occupational therapists, who agreed with the findings on improved appearance (85%), contractures/movement (71%) and a reduction of itchiness (65%) 2 . Anzarut et al 3 and Szabo et al 4 agreed that the effectiveness of PGT has not been firmly established. The use of a randomised control trial to establish the effectiveness of PGT in a setting where the treatment modality is accepted as the most appropriate, could be viewed as unethical.…”

Section: Introductionmentioning

confidence: 99%

An exploration of burn survivors' experiences of Pressure Garment Therapy at a tertiary hospital in South Africa

Pillay

Visagie

Mji

2016

S. Afr. j. occup. ther

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“…Other clinical studies have shown decreased scar height (Candy, Ceceila, & Ping, 2010), as well as significant reduction of redness and thickness among PGTtreated scars (Anzarut, Olson, Singh, Rowe, & Tredget, 2009). Although the exact mechanism of action is unknown, pressure appears clinically to enhance the scarmaturation process (Staley & Richard, 1997).…”

Section: Available Knowledgementioning

confidence: 97%