The medical education landscape has transformed from traditional lecture-based methods to more student-centered learning approaches. This shift is essential for meeting the evolving needs of students and the healthcare environment. Problem-based learning (PBL) stands out among various innovative methods due to its unique educational philosophy and methodology, which have gained widespread recognition and adoption. This paper focuses on applying the PBL teaching model in hepatobiliary surgery clerkship courses, aiming to introduce fresh perspectives and methodologies into medical education. The study's primary objective is to explore the effectiveness of the PBL teaching model in hepatobiliary surgery clerkship courses and its role in fostering a student-centered learning environment. The PBL model emphasizes student engagement and active learning, which is crucial for developing critical clinical reasoning, problem-solving abilities, and teamwork skills. By incorporating the PBL model into the curriculum, the study aims to enhance students' capabilities in handling complex clinical scenarios, thereby improving their overall learning experience. The research methodology includes a comprehensive retrospective analysis of previous literature and experiences from past implementations of the PBL model in medical education. This approach provides a deep understanding of the model's impact, identifying best practices and areas for improvement. The following results were obtained. Findings highlight the significant positive effects of the PBL teaching model on students' clinical reasoning, problem-solving abilities, and teamwork skills in hepatobiliary surgery clerkship courses. Students exposed to the PBL model show substantial improvements in analyzing and solving complex clinical problems, working effectively in teams, and applying theoretical knowledge in practical settings. These results affirm the PBL model's effectiveness in promoting student-centered learning and its potential to significantly enhance students' clinical capabilities. Moreover, the study reveals that the PBL model creates a more engaging and interactive learning environment, encouraging active participation and inquiry-based learning. This shift is instrumental in preparing students for the dynamic nature of clinical practice. In conclusion, applying the PBL teaching model in hepatobiliary surgery clerkship courses significantly advance medical education. It fosters a student-centered learning environment and substantially enhances students' clinical reasoning, problem-solving, and teamwork skills. The study offers valuable insights into the evolution of teaching methodologies in medical education, providing a robust framework for active learning and engagement. The PBL model promises to shape the future of medical education, ensuring it remains responsive to student's needs and the broader healthcare landscape.