The effectiveness of prophylaxis for measles contacts in NSW

Sheppeard, Vicky; Forssman, Bradley; Ferson, Mark J; Moreira, Conrad; Campbell‐Lloyd, Sue; Dwyer, Dominic E.; McAnulty, Jeremy

doi:10.1071/nb08014

Cited by 32 publications

(21 citation statements)

References 6 publications

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“…At the individual level, administration of measles vaccine within 72 hours of initial exposure may avert or modify the clinical course of the illness, and is generally recommended as a preventive tool in elimination settings (Table 1). 1-4 Recent studies have confirmed a benefit from this intervention, with effectiveness of post-exposure immunization ranging between 91%–100%, 54 , 55 corroborating observations made in the pre-elimination era. 56-59 Two studies showing no protection from vaccine prophylaxis were limited by a small sample size 60 or by delayed vaccine administration in relation to measles exposure.…”

Section: Containment Strategies — Guidance Evidence Challenges and mentioning

confidence: 67%

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Public health responses during measles outbreaks in elimination settings: Strategies and challenges

Gastañaduy

Banerjee

DeBolt

et al. 2018

Human Vaccines & Immunotherapeutics

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In late September 2016, the Americas became the first region in the world to have eliminated endemic transmission of measles virus. Several other countries have also verified measles elimination, and countries in all six World Health Organization regions have adopted measles elimination goals. The public health strategies used to respond to measles outbreaks in elimination settings are thus becoming relevant to more countries. This review highlights the strategies used to limit measles spread in elimination settings: (1) assembly of an outbreak control committee; (2) isolation of measles cases while infectious; (3) exclusion and quarantining of individuals without evidence of immunity; (4) vaccination of susceptible individuals; (5) use of immunoglobulin to prevent measles in exposed susceptible high-risk persons; (6) and maintaining laboratory proficiency for confirmation of measles. Deciding on the extent of containment efforts should be based on the expected benefit of reactive interventions, balanced against the logistical challenges in implementing them.

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Section: Containment Strategies — Guidance Evidence Challenges and mentioning

confidence: 67%

“…54 Thus, successful implementation of this strategy requires a close working relationship between healthcare providers and public health specialists and the rapid identification and reporting of cases through active surveillance. 54 , 55 …”

Section: Containment Strategies — Guidance Evidence Challenges and mentioning

confidence: 99%

Public health responses during measles outbreaks in elimination settings: Strategies and challenges

Gastañaduy

Banerjee

DeBolt

et al. 2018

Human Vaccines & Immunotherapeutics

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show abstract

“…Considering the time until immunity in vaccinated individuals develops, two recent studies have shown an effective measles post-exposure prophylaxis (PEP) of 90 . 5% and 100 %, respectively, if conducted within 72 h [18,19]. In individuals who developed measles despite PEP, two other studies observed a maximum time-interval from receiving PEP to the development of measles of y10 days [20,21].…”

Section: Discussionmentioning

confidence: 99%

Measles outbreak in an asylum-seekers' shelter in Germany: comparison of the implemented with a hypothetical containment strategy

Takla

Barth²,

Stöcker

et al. 2011

Epidemiol. Infect.

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SUMMARYIn order to contain a measles outbreak in a German asylum-seekers' shelter, serological testing of all residents was performed, followed by selective vaccination of those with negative test results/ not tested. In this paper we describe the outbreak epidemiologically and then compare the implemented strategy with a hypothetical mass vaccination of all individuals unvaccinated or with unknown vaccination status born after 1970 as recommended by the German Standing Committee on Vaccination in terms of potentially avoided cases, logistics, and costs. Three hundred (70 %) residents participated in the serological testing, of which 39 (13 %) were seronegative. In total, 144 individuals were eligible for vaccination, while a mass vaccination would have targeted 359 persons. However, serological testing was time-and personnel consuming and revealed several logistical problems. Its costs amounted to E90 000, double that of mass vaccination that additionally might have avoided three of the eight cases. Mass vaccination seems the preferred measure for measles outbreak control in such settings.

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“…En effet, plusieurs études ont montré l'efficacité des immunoglobulines chez les sujets à risque dans les six jours suivant l'exposition à un cas confirmé de rougeole [44,[63][64][65] [65].…”

Section: Conduite à Tenir Chez La Femme Enceinteunclassified

Rougeole chez la femme enceinte : mise au point

Guillet

Vauloup‐Fellous

Cordier

et al. 2012

Journal de Gynécologie Obstétrique et Biologie de la Reproducti

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The effectiveness of prophylaxis for measles contacts in NSW

Abstract: Post-exposure immunisation remains an effective tool for preventing secondary cases of measles.

Cited by 32 publications

References 6 publications

Public health responses during measles outbreaks in elimination settings: Strategies and challenges

Public health responses during measles outbreaks in elimination settings: Strategies and challenges

Measles outbreak in an asylum-seekers' shelter in Germany: comparison of the implemented with a hypothetical containment strategy

Rougeole chez la femme enceinte : mise au point

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