The Effectiveness of Single-Dose Fosfomycin as Antimicrobial Prophylaxis for Patients Undergoing Transrectal Ultrasound-Guided Biopsy of the Prostate

Ongün, Şakir; Aslan, Güven; Avkan-Oğuz, Vildan

doi:10.1159/000342370

Cited by 55 publications

(56 citation statements)

References 53 publications

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“…We registered all episodes of symptomatic UTIs that occurred within 1 month after the procedure. A 1-month interval was chosen to increase the likelihood of capturing all symptomatic UTIs attributable to the prostate biopsy [15]. Data were collected by reviewing all ambulatory and hospital medical charts in case of hospitalization for symptomatic UTIs.…”

Section: Data Collection and Microbiological Considerationsmentioning

confidence: 99%

mentioning

confidence: 99%

“…Ongün et al [15] evaluated the efficacy of single-dose FT prophylaxis in comparison with fluoroquinolone-based prophylaxis in patients undergone TR-PB. They found that among all patients with febrile UTI, 5.2 % received prophylaxis with FT while 94.8 % received fluoroquinolonebased prophylaxis [15].…”

mentioning

confidence: 99%

“…They found that among all patients with febrile UTI, 5.2 % received prophylaxis with FT while 94.8 % received fluoroquinolonebased prophylaxis [15]. In other words, FT seems to be an effective drug and a valid alternative for antimicrobial prophylaxis in TR-PB [15]. In 1998, Periti et al [28] found, in a large cohort of patients undergoing transurethral resection of the prostate (TURP), that the incidence of significant postoperative bacteriuria in patients who received FT as prophylaxis was significantly lower than in the amoxicillin and cotrimoxazole groups.…”

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confidence: 99%

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Antimicrobial prophylaxis for transrectal ultrasound-guided prostate biopsy: fosfomycin trometamol, an attractive alternative

Cai

Gallelli²,

Cocci

et al. 2016

World J Urol

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infections (UTIs) occurring within 1 month after TR-PB. The rate of symptomatic UTIs and the rate of ADRs were considered the main outcome measures. Results In the total study population, 72/1109 (6.5 %) patients experienced symptomatic UTIs and among these 11 (0.9 % of total) had urosepsis. Out of 72, 53 (73.6 %) symptomatic UTIs were caused by fluoroquinolone-resistant strains. Out of 632, 10 (1.6 %) patients in Group 1 and 62/477 (12.9 %) patients in Group 2 had symptomatic UTIs (p < 0.001); in particular, 2/632 (0.3 %) patients in Group 1 and 9/477 (1.8 %) patients in Group 2 had urosepsis (p < 0.001). No differences were reported in terms of adverse events (0.6 vs 0.4 %; p = 0.70). A Charlson comorbidity index ≤1 and type of antimicrobial prophylaxis (FT) were found to be associated with a lower probability of symptomatic UTIs in the multivariate model. Conclusions Antibiotic prophylaxis with FT for TR-PB had a lower rate of adverse events and a lower rate of symptomatic UTIs as compared with CIP. Fosfomycin trometamol appears as an attractive alternative prophylactic regimen in prostate biopsies.

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Section: Data Collection and Microbiological Considerationsmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Antimicrobial prophylaxis for transrectal ultrasound-guided prostate biopsy: fosfomycin trometamol, an attractive alternative

Cai

Gallelli²,

Cocci

et al. 2016

World J Urol

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“…Although fluoroquinolones are the most frequently used agents in prophylaxis, the duration of prophylaxis and the choice of antibiotics should be discussed first (34). It has also been reported that the use of fosfomycin trometamol or prophylactic antimicrobial based on rectal swab is currently being investigated as an alternative to antimicrobial prophylactic agents, meta-analyses are being undertaken, and new recommendations on prophylaxis will be included in guidelines to be published in the following years (38,39,40).…”

Section: • Transrectal Prostate Biopsymentioning

confidence: 99%

Multifocal Synchronous Chromophobe, Papillary, and Clear Cell Renal Cell Carcinoma in a Single Kidney

Delto¹,

Hussein²,

Fukuma³

et al. 2018

jus

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Cite this article as: Şen P, Demirdal T. Current Approaches to Surgical Antimicrobial Prophylaxis and Use of Antimicrobial Prophylaxis in Urological Procedures. J Urol Surg 2017;4:159-166. Surgical site infections (SSIs) are the most common and preventable type of healthcare-associated infections in low and middle-income countries and affect one-third of patients that have undergone surgical procedures. As the number of surgical procedures performed increases, the prevention of SSIs becomes more important. It is considered that, it is possible to prevent approximately half of all SSI cases. However, due to the contribution of many factors to the development of SSIs, it may be difficult to effectively prevent these infections, and there is a need to take various preventive measures before, during and after surgery. This review presents the current recommendations on the use of prophylactic antimicrobial agents for the prevention of SSIs and recommendations about antimicrobial prophylaxis in urological procedures. Keywords: Surgical site infections, antibiotics, prophylaxisCerrahi alan enfeksiyonları (CAE) en sık görülen sağlık bakımıyla ilişkili enfeksiyonlar olup önlenebilir olması nedeniyle önem arz etmektedir. CAE önlenmesi için uygulama çeşitleri gittikçe artmakta ve buna bağlı olarak kanıta dayalı müdahale talepleri gün geçtikçe artmaktadır. Bu nedenle önceden yayınlanan kılavuzlara ek güncelleme ihtiyacı doğmaktadır. Yeni ve güncellenmiş öneriler sadece sağlık mensupları için değil, aynı zamanda profesyonel dernek ve kuruluşlar için de bir kaynak olabilme özelliğini taşımaktadır. Bu derlemede CAE önlemeye yönelik profilaktik antimikrobiyal ajan kullanımıyla ilgili güncel önerileri sunmak amaçlanmıştır.

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Comparison of fosfomycin against fluoroquinolones for transrectal prostate biopsy prophylaxis: an individual patient-data meta-analysis

et al. 2017

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The Effectiveness of Single-Dose Fosfomycin as Antimicrobial Prophylaxis for Patients Undergoing Transrectal Ultrasound-Guided Biopsy of the Prostate

Cited by 55 publications

References 53 publications

Antimicrobial prophylaxis for transrectal ultrasound-guided prostate biopsy: fosfomycin trometamol, an attractive alternative

Antimicrobial prophylaxis for transrectal ultrasound-guided prostate biopsy: fosfomycin trometamol, an attractive alternative

Multifocal Synchronous Chromophobe, Papillary, and Clear Cell Renal Cell Carcinoma in a Single Kidney

Comparison of fosfomycin against fluoroquinolones for transrectal prostate biopsy prophylaxis: an individual patient-data meta-analysis

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