The effectiveness of venous thromboembolism prophylaxis interventions in trauma patients: A systematic review and network meta-analysis

Peng, Serena; Zhang, Mandy; Jin, James; MacCormick, Andrew D.

doi:10.1016/j.injury.2023.111078

Cited by 3 publications

(1 citation statement)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Recent studies have examined the effectiveness of VTE prophylaxis in patients with femoral neck fractures undergoing hip arthroplasty and reported superior reductions compared to other agents 7 . On the other hand, the review analysis of VTE risk in patients with hip and lower limb injuries, including eight studies and 17,698 patients, showed that aspirin signi cantly did not reduced the risk of DVT compared to placebo (relative risk (RR): 0.47; 95%CI: 0.05-2.65) 23 . While several studies have reported that aspirin is an effective prophylactic agent for VTE, there have been skeptical evaluations and an identi cation of a lack of high-quality randomized controlled trials supporting its use in this context, necessitating further research 24,25 .…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of Aspirin in Preventing Deep Vein Thrombosis Following Proximal Femoral Fracture Surgery in Japan

Ohmori,

Toda,

Taoka

et al. 2024

Preprint

View full text Add to dashboard Cite

Previous studies have shown that aspirin is effective as a prophylactic agent against venous thromboembolism (VTE) following proximal femoral fractures (PFF). In Japan, there is a lack of evidence regarding its efficacy and safety in this context. Consequently, aspirin is not covered by insurance for the prevention of venous thrombosis. This study aimed to investigate whether continued aspirin use in patients with PFF, who were already taking aspirin for cerebrovascular disease prevention before injury is effective as a prophylaxis for deep vein thrombosis (DVT). We retrospectively analyzed PFF patients (≥ 65 years) who underwent postoperative duplex ultrasonography from January 2010 to December 2023.The study compared patients taking aspirin alone (aspirin group) and those not taking antiplatelet agents or anticoagulants (control group), matched by propensity scores. We enrolled 1064 patients while 161 (15%) were in the aspirin group. After matching, 132 patients were analyzed. DVT incidence was not statistically significant between the aspirin (53) and control groups (57) (OR: 0.72; 95%CI: 0.44–1.20; p = 0.21). Proximal DVT incidence was also similar (OR: 0.83; 95%CI: 0.25–2.73; p = 0.76). Continued aspirin use in PFF patients who were taking aspirin prior to injury did not reduce the incidence of DVT or proximal DVT, indicating no prophylactic benefit.

show abstract

Section: Discussionmentioning

confidence: 99%

Effectiveness of Aspirin in Preventing Deep Vein Thrombosis Following Proximal Femoral Fracture Surgery in Japan

Ohmori,

Toda,

Taoka

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

New Perspectives on Risk Assessment and Anticoagulation in Elective Spine Surgery Patients: The Impact of Ultra-Minimally Invasive Endoscopic Surgery Techniques on Patients with Cardiac Disease

Siciliano,

Lewandrowski,

Schmidt

et al. 2024

JPM

View full text Add to dashboard Cite

The advent of ultra-minimally invasive endoscopic spine surgery, characterized by significantly reduced surgery times, minimal blood loss, and minimal tissue trauma, has precipitated a paradigm shift in the preoperative management of patients with cardiac disease undergoing elective spine procedures. This perspective article explores how these advancements have influenced the requirements for preoperative cardiac workups and the protocols surrounding the cessation of anticoagulation and antiplatelet therapies. Traditionally, extensive cardiac evaluations and the need to stop anticoagulation and antiplatelet agents have posed challenges, increasing the risk of cardiac events and delaying surgical interventions. However, the reduced invasiveness of endoscopic spine surgery presents a safer profile for patients with cardiac comorbidities, potentially minimizing the necessity for rigorous cardiac clearance and allowing for more flexible anticoagulation management. This perspective article synthesizes current research and clinical practices to provide a comprehensive overview of these evolving protocols. It also discusses the implications of these changes for patient safety, surgical outcomes, and overall healthcare efficiency. Finally, the article suggests directions for future research, emphasizing the need for updated guidelines that reflect the reduced perioperative risk associated with these innovative surgical techniques. This discussion is pivotal for primary care physicians, surgeons, cardiologists, and the broader medical community in optimizing care for this high-risk patient population.

show abstract

Thromboprophylaxis to prevent venous thromboembolism in postoperative patients

Ygnacio-Mestanza,

Bazualdo-Fiorini,

Pajares-Huaripata

et al. 2024

Salud, Ciencia y Tecnología - Serie de Conferencias

View full text Add to dashboard Cite

Venous thromboembolism (VTE) is an important cause of morbidity and mortality with a cardiovascular factor. Its appearance is generally determined by risk factors such as surgery. This occurrence can be avoided in some scenarios thanks to the administration of thromboprophylaxis. Therefore, the objective of the study was to analyze the effectiveness of thromboprophylaxis on the incidence of VTE in post-surgical patients. The study was developed thanks to an analytical approach to information, with the PRISMA methodology of systematic reviews, for which works were retrieved through the PUBMED, Science Direct and Scopus search engines, where 20 academic documents were recognized. It is concluded that thromboprophylaxis reduces the incidence of VTE in post-surgical patients; however, it is recommended to continue with studies to determine the most specific anticoagulant according to the type of surgery.

show abstract

The effectiveness of venous thromboembolism prophylaxis interventions in trauma patients: A systematic review and network meta-analysis

Cited by 3 publications

References 39 publications

Effectiveness of Aspirin in Preventing Deep Vein Thrombosis Following Proximal Femoral Fracture Surgery in Japan

Effectiveness of Aspirin in Preventing Deep Vein Thrombosis Following Proximal Femoral Fracture Surgery in Japan

New Perspectives on Risk Assessment and Anticoagulation in Elective Spine Surgery Patients: The Impact of Ultra-Minimally Invasive Endoscopic Surgery Techniques on Patients with Cardiac Disease

Thromboprophylaxis to prevent venous thromboembolism in postoperative patients

Contact Info

Product

Resources

About